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Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Finasteride helps brain function in rats with liver-related brain issues.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.