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In this study, ATP-sensitive potassium channel openers, diazoxide and minoxidil, reduced scratching in cholestatic mice, suggesting these channels may play a role in cholestatic itch, while the channel blocker glibenclamide increased scratching behavior.

This study reported four new cases of NISCH syndrome in a Moroccan family, confirming genetic variability in liver disease severity and suggesting potential benefits from early UDCA therapy.

This review discusses skin changes and dermatoses during pregnancy and reports no clinical findings, emphasizing a need for better understanding of their causes.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

This case report documents a rare instance of Rapunzel syndrome causing biliary obstruction in a 3-year-old girl, highlighting the importance of considering trichobezoar in cholestasis diagnosis.

This review discusses lysophosphatidic acid's role in neuropathic pain and cholestatic itch, highlighting its complex signaling pathways, but reports no new clinical results.

This study analyzed post-marketing data from the U.S. FDA Adverse Event Reporting System and identified both known and new safety concerns for Avacopan, an anti-neutrophil cytoplasmic antibodies-associated vasculitis treatment, emphasizing the need for monitoring during early treatment stages.

This review discusses the evaluation of skin conditions during pregnancy and emphasizes the importance of testing for syphilis, but it reports no new clinical results.

In this case report and literature review, researchers identified a novel mutation in the CLDN1 gene linked to neonatal ichthyosis-sclerosing cholangitis syndrome and found that its phenotype varies widely, suggesting a multidisciplinary approach is crucial for management.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

This study reports that saw palmetto may effectively treat benign prostatic hyperplasia symptoms and potentially stimulate hair growth with generally mild side effects.

This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.

This review discusses the reclassification of pregnancy-related skin diseases and provides a management algorithm but reports no new clinical findings.

This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.

This review summarizes physiologic skin changes during pregnancy and specific pregnancy-related dermatoses but reports no new clinical results.

This study found that polymorphic eruption was the most common pregnancy-related dermatosis, occurring mostly in the third trimester.

This article reviews the physiological skin changes and unique dermatoses in pregnancy, discussing their causes and management, but reports no new clinical findings.

In this study, pigmentary changes were the most common skin changes observed in pregnant women, affecting over 90% of the participants.

In this article, it is explored how pregnancy-related physiologic changes can predispose women to dermatologic conditions affecting well-being, and it highlights the critical role of women’s health nurse practitioners in managing these conditions with attention to safety and efficacy in pregnant patients.

This review discusses recent studies on the hepatotoxic effects of anabolic androgenic steroids and selective androgen receptor modulators, including liver damage, tumors, and related conditions, and reports no new primary research results.

This review reports that pregnancy-specific dermatoses, including AEP, PEP, ICP, and PG, present overlapping clinical features and can significantly impact fetal outcomes, particularly ICP and PG, which are linked to preterm birth and stillbirth.

This study found a variety of dermatological conditions in pregnant women, with Striae Gravidarum being the most prevalent at 48.1%, followed by Linea Nigra at 45.9%.

This review discusses the variety of skin changes and diseases that can occur during pregnancy, categorizing them into physiological changes, non-specific alterations, and pregnancy-specific dermatoses, and reports no clinical results.

This article reviews the specific cosmetology needs and practices related to black skin, identifying associated complications, and emphasizes the need for a robust cosmetovigilance policy but reports no new clinical findings.

This review examines physiological changes and dermatoses during pregnancy and reports no clinical results, highlighting the importance of recognizing these conditions for appropriate management.

Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.

This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.

This article discusses the role of lysophosphatidic acid-induced histamine release in generalized pruritus among patients with primary sclerosing cholangitis and reports no new clinical results.

This article discusses the pseudo 'fringe sign' in frontal fibrosing alopecia, highlighting that it is not solely related to traction, and it reports no new clinical results.

In this case report, the authors describe green hair discoloration in a patient attributed to the use of selenium sulfide.