September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.
January 2018 in “Skin appendage disorders” A woman's hair loss was correctly diagnosed as Lichen planopilaris after initial misdiagnosis, highlighting the usefulness of trichoscopy in diagnosing hair disorders.
September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” CCCA can affect both genders and all ages, and it has a genetic component.
September 2024 in “JAMA Dermatology” Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.
15 citations,
September 2014 in “Journal of The American Academy of Dermatology” Seven patients were misdiagnosed with discoid lupus instead of lichen planopilaris due to similar symptoms, showing the need for careful diagnosis in scarring hair loss conditions.
42 citations,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
1 citations,
June 2022 in “PubMed” Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.
5 citations,
February 2019 in “The New England Journal of Medicine” Certain mutations in the PADI3 gene may increase the risk of developing a type of scarring hair loss common in women of African descent.
1 citations,
July 2018 in “Journal of The American Academy of Dermatology” Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.
September 2021 in “CRC Press eBooks” CCCA is a common hair loss condition in African American women, often inherited and influenced by hairstyling, with unique scalp features detectable by special tools.
4 citations,
August 2010 in “Journal of the American Academy of Dermatology” Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
June 2023 in “JAAD case reports” The document concludes that "hot comb alopecia" is now called "central cicatricial centrifugal alopecia" and its causes are complex.
170 citations,
December 2009 in “Histopathology” The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
80 citations,
March 2000 in “Journal of cutaneous pathology” The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.
2 citations,
February 2021 in “The Journal of clinical and aesthetic dermatology” Understanding the cause of bitemporal hair loss is key to deciding the right treatment.
1 citations,
October 2021 in “Cosmoderma” Hair transplants can work for permanent hair loss if the condition is stable and done carefully.
1 citations,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
January 2022 in “Clinical Cases in Dermatology” A condition called Central Centrifugal Cicatricial Alopecia causes hair loss and scalp burning in middle-aged African women, and it's treated with various medications, hair transplants, and non-drug methods like wigs.
June 2007 in “Journal of Investigative Dermatology” Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
22 citations,
January 2018 in “Experimental Dermatology” The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
November 2012 in “South African Family Practice” The article concludes that early treatment of alopecia is crucial to prevent permanent hair loss.
October 2015 in “CRC Press eBooks” Scalp biopsy and digital phototrichogram help diagnose and manage different types of diffuse hair loss.
April 2021 in “Sohag Medical Journal” Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
4 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.
July 2009 in “Medical & surgical dermatology” Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.
2 citations,
June 2016 in “Dermatologic Clinics” Dermatologists often neglect hair disorders due to complexity and lack of clear treatments, impacting patient care and highlighting the need for better education and interest in this area.
April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
September 2021 in “CRC Press eBooks” Acne keloidalis nuchae is a hair loss condition affecting men of African descent, causing scar-like bumps on the scalp and neck.
16 citations,
July 2013 in “The American Journal of Dermatopathology” Pigmented casts are common in several hair loss conditions and can help diagnose specific types of alopecia.