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120-150 / 1000+ resultsresearch Solubilizing steroidal drugs by β-cyclodextrin derivatives
This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
research Abstract P5-11-11: A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA)
In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.
research Preventive effects of cedrol against alopecia in cyclophosphamide-treated mice
In this animal study, cedrol treatment reduced chemotherapy-induced alopecia in mice by preventing hair follicle damage, while minoxidil did not prevent alopecia under similar conditions.
research The Efficacy and Safety of 17α-Estradiol (Ell-Cranell® alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study
This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
research Calcipotriol/dithranol
research Compatibility of 17-a-estradiol, Caffeine, Clobetasol Propionate, Finasteride Melatonin, Metronidazole, Spironolactone, Tretinoin, and Triamcinolone in Trichosol, a Natural Vehicle for Hair Solutions.
This study evaluated the stability of multiple active ingredients in TrichoSol™ for use in alopecia treatments, finding varying stability durations at room temperature—up to 180 days for some ingredients—supporting its use as a compounding vehicle in personalized therapies.
research 76532 Estetrol (E4) prolongs anagen in healthy and female pattern hair loss hair follicles ex vivo
Estetrol (E4) can help hair grow longer by extending its growth phase.
research Finasteride/spironolactone
research Crown-X: A Novel Menstrual Stem Cell-Based Therapy for Hair Regeneration in Male Pattern Baldness
The research examined Crown-X, a novel formulation containing Menstrual Stem Cells, and found that it promoted significant proliferation of human dermal papilla cells, suggesting its potential as a non-invasive treatment for male pattern baldness. Future clinical trials are necessary to confirm its efficacy.
research Eclipta prostrata (L.) L.: Traditional Use, Phytochemistry, and Pharmacology
This book chapter reviews the taxonomy, traditional uses, pharmacological effects, and safety of Eclipta prostrata, emphasizing its potential therapeutic applications, but it reports no new clinical results.
research Ecklonia cava promotes hair growth
This study suggests that Ecklonia cava, particularly its component dioxinodehydroeckol, may promote hair growth by enhancing dermal papilla and outer root sheath cell activity in culture and mice models.
research Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists
This review updates dermatologists on both FDA-approved and off-label hormonal therapies, including combined oral contraceptives, clascoterone, and spironolactone, used for acne treatment, providing insights into emerging approaches for managing the condition.
research Clinical efficacy of supplement and scalp lotion containing astaxanthin in male androgenetic alopecia
research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error
research Unveiling the Therapeutic Wealth of Eclipta Prostrata: Ethnobotany, Bioactive Compounds, and Biomedical Relevance
This review compiles current knowledge of Eclipta prostrata's botanical details, ethnomedical uses, phytochemical components, and various pharmacological activities, emphasizing its potential for modern pharmaceutical formulations based on its anti-inflammatory, antioxidant, anticancer, and other therapeutic properties.
research Biotransformation of Finasteride (MK-0906) by Selenastrum capricornutum (Green Algae)
Green algae can break down finasteride, reducing environmental harm.
research THERAPEUTIC HOTLINE: Effectiveness of the association of cetirizine and topical steroids in lichen planus pilaris - an open-label clinical trial
This study found that combined therapy with cetirizine and topical steroids stabilized inflammation in most patients with lichen planus pilaris, though one patient experienced cardiac arrhythmia.
research Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α
This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.
research Exploring the mechanism of Platycladi Cacumen in intervening androgenetic alopecia based on network pharmacology, molecular docking, and molecular dynamics simulation
This study predicted that key components of Platycladi Cacumen, such as quercetin and apigenin, may have stable binding interactions with targets involved in androgenetic alopecia.
research Estrogens
research Beneficial Effects of Liver on Cortisone Acetate Toxicity in the Rat.
This study found that feeding desiccated whole liver to immature rats on a synthetic diet largely prevented the negative effects of toxic cortisone acetate doses, unlike known B vitamins.
research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research*
research The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in women
This study found that treatment with cyproterone acetate and ethinyl oestradiol increased hair density in women with diffuse androgen-dependent alopecia, particularly when serum ferritin levels were above 40 μg/l.
research Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer
Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
research Phytochemical Analysis of Eclipta prostrata L. (L.) Leaves
This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
research Case Report. Kerion Celsi effectively treated with terbinafine. Characteristics of kerion Celsi in the elderly in Japan
This case study of a 75-year-old Japanese man with kerion Celsi found that terbinafine treatment was effective and safe, achieving a cure with minimal side effects.
research Foreword
The birth control pill containing ethinylestradiol and chlormadinone may help treat acne and other skin and hair conditions related to hormones.
research Effectiveness of Anastrozole and Cyproterone Acetate in Two Brothers with Familial Male Precocious Puberty
This study found that combined treatment with anastrozole and cyproterone acetate improved the adult height prognosis in testotoxicosis, as observed in two brothers, with good tolerance reported.
research Desenvolvimento de formulação lipídica nanoestruturada utilizando miristato de miristila no carreamento de estradiol
This review discusses the potential of using sustained release systems to increase the effectiveness and reduce side effects of 17-alpha-estradiol in alopecia treatment and reports no clinical results.