TLDR  Liver in the diet reduces cortisone acetate toxicity effects in rats.   
  The study found that administering toxic doses of cortisone acetate to immature rats on a synthetic diet led to retarded growth, alopecia, and death. However, these adverse effects were significantly mitigated by including desiccated whole liver at 10% of the diet. The protective elements in the liver were distinct from known B vitamins.
          
       
           68 citations
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  September 2017   in “Molecular and Cellular Endocrinology”    The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.