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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.