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This review explores the synthesis and potential of azasteroids as novel drugs, discussing challenges in their production and reporting no new clinical results.

This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.

This study found that dimethylpabamidopropyl laurdimonium tosylate, a quaternary ammonium surfactant, adsorbs onto human scalp hair with kinetic and isotherm behaviors fitting specific models, changing hair fiber wettability from hydrophobic to hydrophilic.

This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.

In this study, loading niosomes with Oryza sativa bran extract altered their physical properties, suggesting potential for developing formulations aimed at anti-hair loss products.

This study found that enzymatic phosphorylation of hair keratin increased its capacity to adsorb cationic components like methylene blue and may have practical implications for hair care products.

This study suggests that a hair lotion containing methyl myristate loaded in cationic niosomes may effectively accelerate pigmentation in aged C57BL/6 mice compared to free methyl myristate.

This study found that increasing the pH from 2.0 to 6.0 enhanced the binding of cationic solutes to hair keratin, driven primarily by hydrophobic and electrostatic interactions.

This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.

This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.

This study investigated the penetration of a low-molecular-weight cationic conditioning compound into the hair cortex and suggests it may improve hair's fatigue resistance.

In this study, fluorescence microscopy revealed that a cationic cellulose ether derivative adsorbed onto hair fibers desorbed significantly when treated with sodium dodecylsulfate.

In testosterone-induced AGA mouse models, this study found that a dual-drug-loaded cationic nanoemulsion of minoxidil and finasteride enhanced follicle-associated retention, supporting hair regeneration while reducing systemic absorption and showing good skin compatibility, indicating a promising approach for androgenetic alopecia treatment.

This study found that cationic surfactant-based conditioning systems significantly improve hair combability by forming a stable low-friction film on hair surfaces, reducing friction and enhancing sensory performance compared to standard systems, as confirmed by both instrumental and sensory evaluations.

This study found that cationic surfactant-based conditioning systems significantly reduce friction on hair fibers, improving wet and dry combability by forming a stable film layer on the hair’s surface, as verified by both instrumental and sensory evaluations.

This study found that a 0.5% cationic guar gum and 0.5% anionic surfactant formulation formed stable coacervates with improved adhesion and coverage on damaged hair, suggesting it may enhance the effectiveness of hair conditioning products compared to other ratios.

In this study, researchers developed cationic liposomes encapsulated with keratin to improve the recovery of UV-damaged hair, finding that these liposomes significantly improved keratin penetration and reduced protein denaturation and lipid peroxidation, resulting in smoother hair surfaces compared to keratin solution alone.

This study found that N‐AOHPA was particularly effective as a silicone emulsifier for improving the condition of damaged hair by preventing amino acid dissolution from bleached hair.

This study observed that hyaluronan's transformation into HA·3Ca and its hydrate increases drug absorption by changing its molecular characteristics, influenced by zwitterionic character and acidic pH.

The study found that hybrid nanoparticles incorporating exosomes with cationic liposomes 2X3-DOPE significantly improved the delivery of both messenger RNA and small interfering RNA to rat cardiac mesenchymal stem cells in vitro, achieving up to 100% transfection efficiency for small interfering RNA.

In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.

This study found that a novel in-situ crosslinked self-healing hydrogel made from oxidized Bletilla striata polysaccharide and cationic gelatin enhanced wound healing and showed strong hemostatic performance in animal models, suggesting its potential as an effective wound dressing for skin trauma.

Liposomes with certain properties can effectively deliver drugs deep into hair follicles.

This review discusses various types of hair dyes, their mechanisms of action, molecular structures, application methods, and formulation aspects, but reports no new research findings.

This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.

This study found that cationic lipid-based formulations enhanced the delivery of large molecules into hair follicles in human scalp skin, with potential to reach pharmacologically active concentrations in the hair bulb.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.

This study found that antisense oligonucleotides can significantly reduce androgen receptor expression in cultured human sebocytes and may offer new therapeutic possibilities for androgen-associated skin diseases.