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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The Rotterdam Study aims to understand various diseases in older adults.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Hair loss causes stress and affects mental health; treatment and support needed.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Alopecia is a key indicator of thallium poisoning.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Nerves and chemicals in the body can affect hair growth and loss.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Skin fat helps with body temperature control and has other active roles in health.