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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Finasteride and minoxidil together promote hair growth better than either alone.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Finasteride may improve prostate cancer treatment outcomes.

Trichotillomania, a disorder where people compulsively pull out their own hair, often starts around age 12, is more common in adult females, and can be treated with behavior therapy and medication.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.

Finasteride does not prevent bladder cancer.

Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Analog 23 is a promising compound for prostate cancer treatment.