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    Glossary Capsaicin

    active compound in chili peppers causing heat sensation

    Capsaicin is the active component in chili peppers that gives them their characteristic heat. It works by binding to pain receptors in the mouth and skin, which can cause a burning sensation. Interestingly, capsaicin is also used in topical creams to relieve pain by desensitizing sensory neurons, and some studies suggest it may promote hair growth by increasing blood flow to the scalp.

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    Research 30 of 371

    1. Brachioradial pruritus: Treatment with topical capsaicin Journal of The American Academy of Dermatology · 1993 · 56 citations
    2. A nanocomposite competent to overcome solubility and permeation issues of capsaicin and thiocolchicoside simultaneously in gout management: Fabrication of nanocubosomes Saudi Pharmaceutical Journal · 2024 · 6 citations
    3. Efficacy of a mixed preparation containing piperine, capsaicin and curcumin in the treatment of alopecia areata Journal of cosmetic dermatology · 2022 · 4 citations
    4. Capsaicin: an in-depth review of its chemical properties, health benefits, and challenges in food applications Food Production Processing and Nutrition · 2025 · 2 citations
    5. The Effect of Coapplication of Capsaicin and Minoxidil on the Murine Hair Growth Journal of Clinical Dermatology · 2003
    6. A Hot New Twist to Hair Biology ˜The œAmerican journal of pathology (Print) · 2005 · 174 citations
    7. Autoimmunity: Alopecia Areata Journal of Investigative Dermatology Symposium Proceedings · 2004 · 143 citations
    8. Neural Mechanisms of Hair Growth Control Journal of Investigative Dermatology Symposium Proceedings · 1997 · 101 citations
    9. TRPV1 Function in Health and Disease Current Pharmaceutical Biotechnology · 2010 · 65 citations
    10. Cutaneous Neuroimmune Interactions in Peripheral Neuropathic Pain States Frontiers in Immunology · 2021 · 50 citations
    11. Complementary and Alternative Treatments for Alopecia: A Comprehensive Review Skin appendage disorders · 2018 · 40 citations
    12. Scalp Pruritus: Review of the Pathogenesis, Diagnosis, and Management BioMed Research International · 2019 · 37 citations
    13. Topical and intralesional therapies for alopecia areata Dermatologic therapy · 2011 · 36 citations
    14. Promotion of Insulin-Like Growth Factor-I Production by Sensory Neuron Stimulation; Molecular Mechanism(s) and Therapeutic Implications Current medicinal chemistry · 2008 · 23 citations
    15. A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review Natural Products and Bioprospecting · 2020 · 14 citations
    16. Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle Journal of the Peripheral Nervous System · 2009 · 13 citations
    17. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss JAMA dermatology · 2022 · 11 citations
    18. Next-Gen Therapeutics for Skin Cancer: Nutraceuticals Nutrition and Cancer · 2018 · 10 citations
    19. Herbal Treatment for Dermatologic Disorders Oxidative stress and disease · 2011 · 9 citations
    20. A Hair Growth-Promoting Effect of Chinese Black Tea Extract in Mice Bioscience, Biotechnology, and Biochemistry · 2013 · 3 citations
    21. Role and Mechanisms of Phytochemicals in Hair Growth and Health Pharmaceuticals · 2023 · 2 citations
    22. Clinical Characteristics and Treatment of Acne with Sensitive Skin Dermatologic Therapy · 2023 · 2 citations
    23. Controle de qualidade e análise sensorial em voluntários de xampu esfoliante com extrato hidroalcoólico de Capsicum frutescens L. (Solanaceae) Revista de Ciências Farmacêuticas Básica e Aplicada · 2011 · 2 citations
    24. A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control Experimental Dermatology · 2004 · 2 citations
    25. Role of Phytoconstituents in Augmenting Hair Growth Current Drug Research Reviews · 2026
    26. The use of phytochemicals and other natural materials in the treatment of androgenetic alopecia NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES · 2024
    27. 653 Substance P ameliorates epidermal thickness, basal cell density, and asymmetric stem cell self-renewal in skin with decreased sensory innervation Journal of Investigative Dermatology · 2024
    28. 201 Pain digital biomarker detecting by epidermal biopotential flexible sensor and AI-based system Journal of Investigative Dermatology · 2023
    29. L’importanza della nutrizione nella salute del capello = The importance of nutrition in hair healthcare Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2018
    30. Scalp Sebaceous Physiology Springer eBooks · 2017