research Report on the 11th National Congress AICPE Held in Rimini, Italy, April 12–14, 2024
The 11th AICPE Congress in Rimini was a major event in European aesthetic plastic surgery.
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research Clinical Effectiveness of Finasteride Versus Hydroxychloroquine in the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial
Finasteride was more effective than hydroxychloroquine in treating frontal fibrosing alopecia.
research Efficacy and Safety of Proxalutamide in Severe or Critically Ill COVID-19 Patients: Study Protocol for an Exploratory Trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research Comparative Efficacy of Topical Finasteride (0.25%) in Combination With Minoxidil (5%) Against 5% Minoxidil or 0.25% Finasteride Alone in Male Androgenetic Alopecia: A Pilot, Randomized Open-Label Study
Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Hair Loss Associated with COVID-19: Problems and Solutions
COVID-19 can cause temporary hair loss due to stress and inflammation.
research Occurrence of Klinefelter Syndrome Mosaic 45,X/46,XY/47,XXY/48,XXYY/48,XXXY and Primary Hyperparathyroidism
A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.
research Effect of Platelet Counts and Activator in Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia, Split-Head Comparison: A Randomised, Double-Blind Study
Higher platelet counts and activators in PRP improve hair density and thickness in treating hair loss.
research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition
Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
research Microneedles in the Clinic: A Comprehensive Review of Clinical Studies and Applications
Microneedles are being used and tested for various medical and cosmetic treatments.
research Seaweeds as Source of Bioactive Substances and Skin Care Therapy: Cosmeceuticals, Algotherapy, and Thalassotherapy
Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
research Budesonide for Maintenance of Remission in Crohn's Disease
Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.
research Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma
Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
The study identified Type XVII collagen (COL17) as a crucial regulator of epidermal cell proliferation in the interfollicular epidermis (IFE) of both neonatal and aged mice. In neonatal mice, the absence of COL17 led to transient hyperproliferation due to disrupted Wnt signaling, which was reversible by replenishing COL17. In aged skin, loss of COL17 caused by inactive atypical protein kinase C signaling resulted in hyperproliferation, which could be suppressed by overexpressing human COL17. The research highlighted COL17's role in maintaining skin homeostasis and suggested its potential as a target for anti-aging treatments. However, the study faced limitations, including discrepancies between in vitro and in vivo results and a small sample size of patients with COL17A1 mutations, indicating a need for further investigation.
research Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage
Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.
research Immunosuppressive Treatment for Proliferative Lupus Nephritis
Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.
research The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments
New genetic discoveries may lead to better treatments for alopecia areata.
research Oral Isotretinoin for Acne
Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial
Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.
research Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata
Certain HLA class II alleles increase or decrease the risk of alopecia areata.
research The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research Alopecia in Patients with COVID-19: A Systematic Review and Meta-Analysis
Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.
research The Genetic Architecture of Alopecia Areata
Genetic discoveries are leading to new treatments for alopecia areata.
research Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases
Thiopurines help treat IBD but require genetic testing to avoid side effects.
research Ovarian Surgery for Symptom Relief in Women with Polycystic Ovary Syndrome
Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.
research Evaluation of the Relationship Between Alopecia Areata and Viral Antigen Exposure
Hepatitis B virus exposure may be linked to increased risk of alopecia areata.
research Heat Treatment Increases the Incidence of Alopecia Areata in the C3H/HeJ Mouse Model
Heat treatment increases hair loss in certain mice.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review
There is a significant need for better-validated quality of life tools in dermatology.