48 citations
,
August 1981 in “American Journal of Veterinary Research” This study demonstrates that glucocorticoid hepatopathy in Beagle dogs led to rapid and lasting clinical, morphologic, and biochemical changes, which may aid in the future diagnosis and prognosis of similar conditions.
44 citations
,
September 2011 in “Journal of Pediatric Gastroenterology and Nutrition” This study reported four new cases of NISCH syndrome in a Moroccan family, confirming genetic variability in liver disease severity and suggesting potential benefits from early UDCA therapy.
January 2020 in “JAAD case reports” Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
November 2025 in “FEBS Open Bio” In this study, the researchers using Shh-GFP+/- mice found that cyclophosphamide-induced alopecia involves the JAK/STAT1 pathway, where STAT1 binds the Shh gene promoter, decreasing Shh-expressing cells in hair follicles. Treatment with JAK inhibitors helped rescue hair loss, implicating the JAK/STAT1 pathway in this process.
5 citations
,
August 2015 in “Sultan Qaboos University medical journal” This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.
11 citations
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October 2001 in “Dermatologic Clinics” In this study, subcutaneous recombinant human IL-12 showed a 43% partial response rate in early-stage mycosis fungoides patients refractory to previous treatments, with generally mild to moderate adverse events reported.
April 2026 in “Almanac of Clinical Medicine” In this study, pemphigus vulgaris patients treated with high-dose prednisolone developed symptoms similar to those seen in corticosteroma, such as weight gain and muscle weakness, with increased risks of arterial hypertension and glucose metabolism disorders after 6 months of therapy.
January 2025 in “Cell Communication and Signaling” This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.
April 2020 in “Journal of the Endocrine Society” This case report details an atypical presentation of Hodgkin's lymphoma in an 87-year-old man, where severe hypercalcemia and mental status changes prompted further investigation and diagnosis.
1 citations
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December 2013 in “International Journal of Dermatology” This correspondence article discusses the association between acquired silky African hair, malnutrition, and chronic diseases but reports no new research findings.
March 2024 in “Cancer Research” This study found that eliminating senescent cells using senolytic drugs effectively prevented and reversed paclitaxel-induced peripheral neuropathy in mice.
26 citations
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April 2007 in “Journal of clinical oncology” June 2026 in “Journal of Investigative Dermatology” This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.
April 2008 in “Companion Animal” This article is a self-assessment by Rosa Angela Ragni and Kenneth Smith, reporting no new results.
In this study using C3H/HeJ mice, a single subcutaneous injection of the fusion protein PTH-CBD increased anagen hair follicle counts and promoted hair regrowth comparably to daily oral ruxolitinib, potentially by enhancing beta-catenin production and stimulating anagen transition.
16 citations
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June 1992 in “PubMed” In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.
March 2019 in “Journal der Deutschen Dermatologischen Gesellschaft” This clinical letter identifies Rothmund-Thomson syndrome type 2 as a rare cause of chronic wounds, but provides no new experimental findings.
This case report describes a 12-year-old male dog with hepatoid cell carcinoma, showing significant health improvement after a month of bioregulatory therapy, including gastroenteropathy resolution, hair regrowth, and restored vision.
73 citations
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May 1976 in “JAMA” This case report associates severe zinc deficiency with long-term total parenteral nutrition, suggesting the need for trace element supplementation in such nutritional management.
36 citations
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February 2004 in “Veterinary Dermatology” This report describes three cases of feline exudative dermatitis in neutered European cats, associated with lymphangiosarcoma, confirmed by histopathological and ultrastructural findings.
January 2023 in “Discovery medicine” This study found that Cepharanthine may mitigate doxorubicin-induced senescence by reducing SA-β-Gal activity and restoring autophagy in cell models, offering insights for antiaging drug development.
2 citations
,
February 2020 in “Chinese Medical Journal” This case report highlights the missed diagnosis of systemic lupus erythematosus in a pregnant woman, leading to her death despite treatment efforts after cesarean section and epidural anesthesia complications.
2 citations
,
May 2008 in “Journal of Clinical Oncology” This study found that patients with unresectable melanoma treated with AZD6244 experienced skin reactions, including depigmentation and papulopustular rashes, in patterns similar to those caused by EGFR inhibitors.
1 citations
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March 2022 in “Cureus” This case report discusses a 25-year-old woman diagnosed with acne necrotica varioliformis and highlights the diagnostic challenges and potential associations with systemic diseases.
5 citations
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January 2024 in “JID Innovations” In this study, researchers identified significant differences in protein expression patterns in scalps affected by central centrifugal cicatricial alopecia, notably upregulation of immune pathways and fibrosis markers and downregulation of metabolic proteins, suggesting unique disease mechanisms and potential therapeutic targets.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.
9 citations
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October 2015 in “Postgraduate Medical Journal” This case study illustrates the classic dermatological signs of scurvy in a man with unusual dietary habits, showcasing the importance of recognizing and treating vitamin C deficiency in marginalized populations.
4 citations
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January 2015 in “Türk Patoloji Dergisi” This review discusses the skin manifestations of endocrine diseases and reports no new clinical findings, emphasizing the importance of recognizing these signs for early diagnosis.
4 citations
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June 1980 in “American Journal of Clinical Nutrition” Malnutrition can change hair color due to altered copper and zinc levels.
19 citations
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August 2020 in “Gastroenterology report” This review discusses the characteristics and challenges in treating Cronkhite–Canada syndrome but reports no new clinical findings, emphasizing the need for better understanding and uniform treatment approaches.