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A gene mutation worsens skin irritation in mice due to a lack of certain fats.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Removing part of the vitamin D receptor stops vitamin D from working properly.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Lowering testosterone speeds up wound healing in male mice.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.