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This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.

This study developed a metal-free method for synthesizing sulfinimidate esters, showcasing their potential as versatile intermediates for enantioselective bond formation under mild conditions.

This case report describes the first documented instance of epidermal nevus syndrome caused by a postzygotic KRAS G12C mutation in a three-year-old Japanese girl.

This study explored the effects of a common Hutchinson-Gilford progeria syndrome mutation in an inducible mouse model, revealing skin abnormalities similar to those in affected patients.

In this study, the authors found that rabbit hair material ground for 8 hours had better suitability and histocompatibility for injectable soft tissue augmentation compared to other tested formulations.

This review discusses drug repositioning for cardiometabolic disorders and reports no new clinical findings; the authors emphasize its potential benefits, such as known safety profiles and reduced development costs compared to new drug development.

This study investigated peptidergic nerve fibers in sinus hair follicles of various mammals and found that CGRP fibers were more densely distributed than SP fibers across different regions of the follicles.

This study introduced the BASP classification, a new system for categorizing pattern hair loss in both men and women, and applied it to analyze 2213 Korean subjects.

This study found that soups with 5% and 10% hibiscus flower were more desirable in sensory attributes and had higher β-carotene content compared to the control soup.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

Hair follicles stored in a special medium had the highest survival rate, and "plucked" follicles and follicular units showed better growth after transplant.

This study reported an increase in allergic contact dermatitis cases linked to natural products, particularly propolis and marigold, with a higher incidence in women than men.

This study reports that transplantation of an ESCs-collagen-chitin biomimetic membrane leads to successful in situ skin regeneration, including hair follicle cell proliferation and formation of dermatoglyphs, in nude mice with full-thickness skin defects.

In this study, researchers identified a novel KRT74 gene mutation associated with autosomal recessive pure hair and nail ectodermal dysplasia in a Pakistani family, expanding the known genetic causes of the disorder.

This study identified two prevalent and one newly proposed founder LIPH mutations in Japanese patients with autosomal recessive woolly hair/hypotrichosis and associated these mutations with different severities of hair loss.

This study found that chronic stress may inhibit hair follicle growth and melanogenesis in mice through modulation of the central HPA axis, with C57BL/6 mice appearing most sensitive to these effects.

In this study, incorporating cetirizine into transferosome formulations significantly enhanced hair growth in mice and boosted IGF-1 and VEGF levels, suggesting that this method could be a promising alternative to traditional hair growth treatments, though further studies are needed to confirm its safety and suitability.

This study found that storing horse hair follicles in RNAlater® at cool or room temperature for up to a week did not affect RNA integrity, suggesting it allows for flexible sample transport without immediate freezing.

This study found that synthetic RNA and DNA trigger significant increases in certain chemokines in human keratinocytes, predominantly via NF-κB activation, without evidence of alternative splicing, suggesting other regulatory pathways may be involved.

In this study, researchers evaluated male-pattern hair loss treatments using RNA and microRNA expression profiling in 91 male participants, identifying 52 differentially expressed genes and suggesting a potential role for personalized treatment based on genetic analysis to monitor and predict treatment efficacy and compliance.

This study found that the novel bacteriophage Halo KS-7 shows strong antibacterial activity against carbapenem-resistant Klebsiella pneumoniae and significantly promotes wound healing in mice, making it a promising biocontrol agent for managing multidrug-resistant infections.

This study found that selectively inactivating ribonucleotide excision repair in mouse epidermis leads to DNA damage, keratinocyte intraepithelial neoplasia, and squamous cell carcinoma, indicating a potential tumor-promoting mechanism related to compromised genome maintenance.

This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.

In this four-year study, pediatric patients with inoperable plexiform neurofibromas and type 1 neurofibromatosis treated with selumetinib frequently experienced dermatologic side effects, which required tailored management strategies and sometimes led to treatment suspension, potentially affecting tumor regrowth.

This study found that single-born cashmere goats had higher birth weights, pre-weaning growth rates, and superior cashmere production attributes compared to twin-born goats, despite twin-born goats achieving compensatory growth post-weaning.

This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.

This study characterizes a type II keratin intermediate filament gene family involved in early sheep follicle differentiation, detailing gene expression patterns and sequences in hair cortical cells.

This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.

Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.