July 2019 in “Facial Plastic Surgery Clinics of North America” New techniques and technologies are improving facial plastic and reconstructive surgery.
May 2015 in “Journal of Investigative Dermatology” In this study, Wnt-3a was found to play an important role in partially maintaining and expanding epithelial skin stem cells in vitro, suggesting potential for in vitro stem cell culture without feeder cells.
December 2014 in “Annals of psychophysiology” This study reported that chronic use of performance-enhancing drugs significantly altered users' personalities and physical attributes, raising concerns about whether the perceived benefits outweigh the costs.
January 2012 in “Journal of the Dermatology Nurses’ Association” The document explains hair growth, hair loss types, and other hair-related terms.
1113 citations
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August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
264 citations
,
January 2008 in “Journal of biomedical optics” This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.
150 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” This article provides contact information for Bruce A. Morgan and features no new research findings.
140 citations
,
August 2011 in “Biomaterials” This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
138 citations
,
May 2000 in “Maturitas” This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.
115 citations
,
February 2016 in “Nature Communications” The authors concluded that the dermal response to epidermal Wnt/β-catenin signaling depends on distinct fibroblast lineages, with each responding to different paracrine signals such as Hedgehog and TGF-β.
92 citations
,
January 1999 in “Physics in Medicine and Biology” This study developed and validated a computational model to optimize skin precooling methods for minimizing thermal damage during laser procedures.
76 citations
,
May 2007 in “Menopause International” This review discusses the relationship between estrogen deficiency and skin aging in postmenopausal women, noting potential benefits of estrogen use on skin collagen and elasticity, but reports no new clinical results.
70 citations
,
January 2000 in “Hormone Research in Paediatrics” This article reviews the characteristics and classification of SAHA syndrome and its relationship with other conditions, without presenting new clinical findings.
59 citations
,
January 2015 in “Nanoscale” In this study, polymeric micelles containing retinoic acid were found to improve targeted delivery to hair follicle structures in human skin more efficiently than a marketed retinoic acid gel, suggesting potentially safer and more effective acne treatment.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
53 citations
,
June 1977 in “Lancet” In this study, jaw wiring led to significant weight loss in patients with severe obesity, but two-thirds regained weight after the wires were removed.
48 citations
,
September 2017 in “Frontiers in Bioscience” This review explores the role of nanotechnology in wound healing, highlighting its potential through antimicrobial properties, selective inflammatory action, angiogenesis promotion, and its use in drug and gene delivery.
47 citations
,
September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.
47 citations
,
September 2008 in “British Journal of Dermatology” This study found that women with androgenetic alopecia experience diffuse hair loss due to a decrease in terminal hairs and an increase in vellus hairs per follicular unit.
44 citations
,
October 2011 in “Gynecological Endocrinology” This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.
42 citations
,
April 2008 in “Acta materialia” This study investigated the tensile response and morphological changes of different ethnic hair types using AFM, showing variations between virgin, chemically damaged, and conditioner-treated Caucasian hair under different conditions.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
37 citations
,
January 1997 in “Clinics in Dermatology” This study found that women with androgenetic alopecia and alopecia areata had significantly lower serum ferritin levels compared to women without hair loss.
33 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
32 citations
,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.
29 citations
,
May 2020 in “npj Regenerative Medicine” This review discusses the role of the immune niche in hair follicle regeneration and its impact on different forms of alopecia, highlighting research gaps and potential therapeutic strategies.
27 citations
,
March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
24 citations
,
May 2009 in “Veterinary Dermatology” This review discusses the dermatology of nonhuman primates and emphasizes the need for a cohesive approach to study and report their dermatologic diseases, without assuming similarities to human or other veterinary conditions.