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    Glossary BRAF inhibitors

    drugs that block mutated BRAF protein to treat cancer

    BRAF inhibitors are a class of drugs designed to block the activity of the BRAF protein, which is involved in sending signals inside cells and can contribute to cancer growth when mutated. These inhibitors are particularly used in treating certain types of melanoma and other cancers with specific BRAF mutations, helping to slow down or stop the progression of the disease.

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    Research 30 of 353

    1. BRAF Inhibitor Dabrafenib in Patients with Metastatic <i>BRAF</i>-Mutant Thyroid Cancer Thyroid · 2014 · 188 citations
    2. Cutaneous adverse effects of BRAF inhibitors in metastatic malignant melanoma, a prospective study in 20 patients. Journal of the European Academy of Dermatology and Venereology · 2014 · 31 citations
    3. Network pharmacology and molecular docking analysis on potential molecular targets and mechanism of action of BRAF inhibitors for application in wound healing Journal of Cellular Biochemistry · 2023 · 11 citations
    4. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    5. Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects PLOS ONE · 2021 · 3 citations
    6. Melanotic pigmentation in excisional scar of melanoma patient who received BRAF and MEK inhibitors Journal of The American Academy of Dermatology · 2018 · 1 citations
    7. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    8. Cutaneous manifestations of dabrafenib (GSK2118436): a selective inhibitor of mutant BRAF in patients with metastatic melanoma British Journal of Dermatology · 2012 · 173 citations
    9. Abstract 1677: Epithelial hyperplasia induced by a selective B-Raf inhibitor, WYE-130600 Cancer Research · 2010 · 1 citations
    10. 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma Journal of Investigative Dermatology · 2016
    11. Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis Acta neuropathologica communications · 2019 · 29 citations
    12. Alopecia due to chemotherapeutics, hedgehog inhibitors, targeted antibody therapies and immune checkpoint inhibitors Deleted Journal · 2024
    13. Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails American Journal of Clinical Dermatology · 2018 · 179 citations
    14. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
    15. Cutaneous Drug Eruptions Associated with the Use of New Oncological Drugs 2012 · 29 citations
    16. Cutaneous toxicities of new treatments for melanoma Clinical & Translational Oncology · 2018 · 25 citations
    17. The spectrum of cutaneous adverse events during encorafenib and binimetinib treatment in B‐rapidly accelerated fibrosarcoma‐mutated advanced melanoma Journal of the European Academy of Dermatology and Venereology · 2018 · 21 citations
    18. Management of Dermatologic Toxicities Journal of the National Comprehensive Cancer Network · 2015 · 12 citations
    19. Dermatologic adverse events associated with chemotherapy and targeted anticancer therapy Dermatology Review · 2016 · 4 citations
    20. Diseases of the Canine Prostate Gland Veterinary medicine and science · 2022 · 1 citations
    21. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    22. The Influence of Flightless I: Regeneration versus Wound Healing Journal of Investigative Dermatology · 2011 · 1 citations
    23. Tombo em João Pessoa dá força a Memorial da Arquitetura Paraibana Projeto: revista mensal de arquitetura · 2008
    24. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    25. The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis Cutaneous and Ocular Toxicology · 2018 · 9 citations
    26. Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy? Experimental Dermatology · 2006
    27. Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma 2016 · 32 citations
    28. Management of Toxicities of Targeted Therapies Elsevier eBooks · 2018 · 2 citations
    29. Sorafenib combined with hepatectomy in patients with intermediate-stage and advanced hepatocellular carcinoma Archives of Medical Science · 2017 · 16 citations
    30. Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma Clinical cancer research · 2004 · 234 citations