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The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Dutasteride effectively treats benign prostatic hyperplasia, improving symptoms and quality of life.

Anti-androgen therapy may boost immunity but increases injection site pain in vaccinated patients.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.