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The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Certain skin conditions may indicate or increase the risk of Parkinson's disease.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Both treatments for pemphigus foliaceus in dogs are effective, but combination therapy has more side effects.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

A blood pressure drug, diltiazem, may also help treat influenza.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.