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The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Selenium can be toxic to animals, causing serious health issues, especially in horses.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.

Vitamin D3 may protect rat hair follicles from radiation damage.

Some chemicals absorbed through the skin can cause serious health problems.

Rituximab effectively treated a woman's bone lymphoma that was resistant to other treatments.

Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Chemotherapy toxicity might be reduced by using DNA neutralizing agents.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.

Pumpkin seed oil promotes hair growth and improves hair texture without harmful effects.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Many people in Saudi Arabia use vitamin D supplements, but few experience toxicity, showing the need for professional guidance when taking these supplements.

Platinum compounds used in cancer treatment can cause serious side effects like organ damage and hair loss.

Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Linoleic acid (Vitamin F) can help protect against the harmful effects of acrylamide.

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.

Stem cells from hair follicles in a special gel show strong potential for bone regeneration.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.