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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Doctors need to be better prepared to assess and treat obesity in patients.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Mice with CBS deficiency are healthier on a low-methionine diet.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Testosterone improves mood and thinking skills; finasteride has no effect.

Many young Australian women think they have PCOS, but only a few are diagnosed correctly, causing unnecessary worry.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.