Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This pilot study suggests that high-dose testosterone plus finasteride increased lower-extremity bone mineral density in men with impaired gait and low to low-normal testosterone following chronic incomplete spinal cord injury.

This study suggests that inactivation of β-catenin is necessary for chick retina regeneration, as it allows cells to enter the cell cycle during injury and promotes regeneration without needing FGF2.

This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.

Blocking DPP4 can help prevent fat loss and skin fibrosis.

This study found that small molecule AP-1 inhibitors may selectively target SMO inhibitor-resistant basal cell carcinoma cells characterized by specific markers, potentially enhancing combinatorial cancer therapies.

This study identified a novel pathogenic splice-site variant of the LAMB3 gene in patients with junctional epidermolysis bullosa, highlighting the importance of gene sequencing for diagnosis.

This study identified a new FAK isoform, FAKΔe4, which is regulated by ECM stiffness and affects cell migration, invasion, and mechanosensing in human-derived data and engineered models.

This study found that the absence of vitamin D receptor signaling in mice impairs the inflammatory response to skin injury, particularly affecting macrophage recruitment and granulation tissue formation.

This study found that 808 nm laser photobiomodulation altered mitochondrial respiration and enhanced osteogenic protein expression in human dental pulp stem cells, with the effects being dose-specific and more pronounced at 15 J/cm².

In this placebo-controlled study, finasteride significantly improved symptoms, reduced prostate size, and increased urine flow rate in patients with moderately symptomatic BPH over two years.

This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.

Mutations in β1 integrins cause embryonic death but have milder effects on skin.

This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.

This study demonstrated that VD3 significantly enhanced the proliferation and differentiation of epidermal stem cells in a murine skin defect model, leading to improved wound healing, potentially through activation of the PI3K signaling pathway.

In this study, human bone marrow mesenchymal stem cells were found to affect skin adnexa growth in diabetic burn-injured rats, but the effects were not statistically significant.

This study found that treating a 3D hair dermal papilla model with rice bran extract and electromagnetic fields increased melanogenesis, suggesting potential for vitiligo and white hair therapies.

This study found that transplanting genetically modified dermal fibroblasts into full-thickness skin defects in rats led to the formation of hair follicles with mature pilosebaceous systems by 16 weeks.

This study found that the acceleration of endothelial to mesenchymal transition due to loss of Notch signaling led to delayed wound healing and increased scarring in skin wounds.

This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.

This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.

This review discusses three newly identified forms of epidermolysis bullosa related to mutations in DST-e, EXPH5, and ITGA3, offering insights into their genetic and clinical characteristics but reports no new clinical results.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

In this study, Lespedeza bicolor extract was found to enhance dermal papilla cell proliferation and extend the anagen phase in mice, suggesting its potential as a treatment for alopecia.

This review discusses recent advances in understanding the molecular landscape of the dermal papilla, particularly focusing on Blimp1's role in hair follicle development and potential therapeutic targets for hair regeneration, but presents no new clinical results.

This study found that dermal EZH2 plays a crucial role in controlling fibroblast differentiation by regulating Wnt/β-catenin and retinoic acid signaling during skin development.

This case report from the study describes a dog suffering from dermatophytosis caused by Microsporum canis, presenting with alopecia on the neck and ear, illustrating the zoonotic risk of these fungal infections in both animals and humans, particularly in hot and humid climates.

This study found that DNA methylation may regulate the differential expression of the BMP7 gene in Hu sheep lamb skin of different patterns, and it influences the proliferation and cell cycle of dermal papilla cells, with demethylation treatment increasing BMP7 expression and cell proliferation.

This study explored the effects of DPP, a 15-PGDH inhibitor, on human follicle dermal papilla cells damaged by dihydrotestosterone and observed that DPP enhanced wound healing, reduced reactive oxygen species, and increased hair growth in ex vivo human hair follicle cultures.

TEDAR is crucial for skin cell differentiation and barrier formation.

Wnt-10b helps skin cells and hair grow.