research P175 The effects of biotin supplementation on alopecia in rats which were administrated to valproic acid
Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
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30 / 1000+ resultsresearch Effectiveness of Biotin Supplementation for Hair Growth in Patients with Alopecia: A Systematic Review
This systematic review found no consistent evidence supporting the effectiveness of biotin supplementation for alopecia treatment unless there is a documented deficiency.
research Biotin beware: Perils of biotin supplementation: Response to: “The epidemiology, impact, and diagnosis of micronutrient nutritional dermatoses. Part 2: B-complex vitamins”
This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.
research Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation
This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.
research Response to Falotico et al’s “Biotin beware: Perils of biotin supplementation”
This review discusses the risk factors, clinical presentation, diagnosis, and management of dermatoses linked to B-complex vitamin deficiencies, including biotin, but does not address risks from over-supplementation.
research Natural Hair Supplements: Biotin and Collagen
Biotin and collagen may improve hair health.
research The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
This review evaluates biotin's popularity and its purported benefits for hair improvement but finds no clinical evidence supporting its efficacy.
research Evidence Review: Natural Hair Supplements: Biotin and Collagen
Biotin and collagen may help improve hair health.
research Effect of dietary biotin supplementation on sow reproductive performance and soundness and pig growth and mortality.
In this study, dietary biotin supplementation showed no significant benefit on reproductive performance in sows or pre-weaning growth and mortality in piglets.
research The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid
In this study on rats, valproic acid was associated with reduced biotinidase enzyme activity and higher alopecia rates, but biotin supplementation did not significantly affect alopecia occurrence.
research Assessment of biotin supplementation among patients in an outpatient dermatology clinic
This study found that biotin supplementation is common among patients at a dermatology clinic despite a lack of evidence for its dermatologic benefits and potential interference with lab tests.
research Efficacy and Safety of a Food Supplement Containing L-cystine, Serenoa repens Extract and Biotin for Hair Loss in Healthy Males and Females. A Prospective, Randomized, Double-blinded, Controlled Clinical Trial
In this clinical trial, supplementation with Lambdapil® Anti Hair Loss capsules for 6 months significantly improved hair resistance and volume in women and increased the anagen/telogen hair ratio in men, indicating enhanced hair growth compared to the placebo group.
research Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements
This study found that temporary hair loss is common after laparoscopic sleeve gastrectomy, and biotin supplementation showed low effectiveness in preventing this hair loss.
research Clinical Evaluation of Intradermal Platelet Rich Plasma Administration along with Oral Biotin Supplement for the Management of Androgenetic Alopecia in Adult Males: A Randomised Clinical Tria
This study found that intradermal administration of PRP combined with oral biotin significantly increased hair regrowth in men with androgenetic alopecia, without notable side effects.
research Effect of Primary Biotin Deficiency on the Skin of Germ-Free and Conventional Mice Fed a Purified Biotin-Deficient Diet without Supplementation with Egg White.
This study found that germ-free mice on a biotin-deficient diet exhibited significant weight loss and severe alopecia, unlike conventional mice on the same diet.
research Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice
This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.
research Serum biotin levels in women complaining of hair loss
This study found that 38% of women with hair loss had a biotin deficiency, suggesting oral biotin supplementation should be based on confirmed biotin deficiency rather than as a general treatment.
research Serum biotin and zinc in male androgenetic alopecia
This study found that male androgenetic alopecia patients had significantly lower serum zinc levels and suboptimal biotin levels compared to healthy controls, suggesting the potential value of zinc and biotin supplementation.
research Biotin Deficiency in Telogen Effluvium: Fact or Fiction?
This study found no significant difference in serum biotin levels between patients with telogen effluvium and control subjects.
research Prevalence of Biotin Overconsumption for Beauty Purposes Influenced by Social Media: A Cross-Sectional Study
This study observed that social media significantly influences biotin supplement use among young women in Pakistan, often outweighing professional medical advice.
research Biotin for Hair Loss: Teasing Out the Evidence.
In their review, the authors found no strong evidence supporting biotin's effectiveness as a hair supplement, noting a significant disparity between its popularity and scientific backing, with available studies showing no substantial benefit over placebo.
research A Review of the Use of Biotin for Hair Loss
This review discusses the use of biotin for hair and nail growth, noting clinical improvement in cases with existing pathologies, but concludes there is insufficient evidence supporting its benefits for healthy individuals.
research Supplement use among women experiencing hair loss
Most women with hair loss take more supplements than average, but these often don't help and can be risky and costly.
research Trends in hair, skin, and nails supplement use: Data from the National Health and Nutrition Examination Survey 2011-2020
This observational study using NHANES data from 2011 to 2020 found that the use of hair, skin, and nails supplements almost doubled, particularly among younger, female, Black, and Hispanic/Latino individuals, despite limited evidence on their efficacy and potential health risks.
research Unknown safety profile of ingredients in hair supplements: A call to action for improved patient safety
This source highlights concerns about the safety and efficacy of dietary supplements marketed for hair loss, citing a lack of FDA testing and potential risks such as adverse side effects, interference with medical tests, and withholding of ingredient information.
research Nutrition, Oral Supplements, and Alternative Therapies for Hair Loss
Proper nutrition and alternative therapies can help manage hair loss.
research Nutritional supplements
This source highlights the increasing use of nutritional supplements among patients with androgenetic alopecia, noting positive effects on hair thickness and density in controlled trials, while emphasizing the need for further research to understand their safety and efficacy.
research Biotin and biotinidase deficiency
This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
research Alopecia and periorificial dermatitis in biotin-responsive multiple carboxylase deficiency
This case study of three siblings highlights the importance of recognizing dermatologic signs—alopecia and periorificial dermatitis—for early diagnosis and treatment of biotin-responsive multiple carboxylase deficiency.
research Biotin Deficiency in an Infant Fed with Amino Acid Formula
This case report describes a 5-month-old Japanese infant with biotin deficiency, where daily oral biotin supplementation led to significant improvements in skin conditions and hair growth.