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The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Thymosin β4 helps increase hair growth in Cashmere goats.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.

Non-coding RNAs could help detect and treat radiation damage.

Bleaching damages hair by reducing the quality of keratin and keratin-associated proteins.

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

Older men with lower levels of available testosterone are more likely to be frail.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.

Rosemary and kalonji seeds can improve hair health and treat hair conditions.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.

A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.