3 citations
,
November 2017 in “International Journal of Cosmetic Science” This study found that increasing the pH from 2.0 to 6.0 enhanced the binding of cationic solutes to hair keratin, driven primarily by hydrophobic and electrostatic interactions.
1 citations
,
October 2025 in “Scientific Reports” This study investigated the Mandarin duck as a model for understanding lifelong developmental changes, finding that male sail feather morphogenesis involves a combination of local morphogenetic programs, epigenetic regulation, and hormonal cues, with increased female estrogen levels observed before the mating season.
16 citations
,
October 2009 in “Xenobiotica” This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.
1 citations
,
November 2021 in “Ultrasonography” This study found that applying low-intensity ultrasound enhanced hair growth on the treated area of mice with androgenic alopecia, potentially by affecting the action of finasteride.
In this study, researchers investigated the impact of a bioactive peptide derived from amphibians on hair follicle regeneration in diabetic skin, focusing on its potential to enhance wound healing and reduce infection risk.
19 citations
,
December 2015 in “Journal of Investigative Dermatology” This study found that keratin 17 expression is initially down-regulated and later strongly up-regulated by ionizing radiation in a rat model, with p53 repressing early transcription.
January 2023 in “Bioorganičeskaâ himiâ” This study found that a new deoxycholic acid derivative may offer a similar prostatoprotective effect to finasteride with lower toxicity in rat models.
4 citations
,
January 2023 in “Journal of Clinical Investigation” This study identified a recurrent mutation in the endothelin receptor type A associated with mandibulofacial dysostosis with alopecia, and proposed a mechanism involving increased ligand affinity due to structural changes.
1 citations
,
February 2023 in “Russian Journal of Bioorganic Chemistry” In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.
July 2026 in “Journal of Dermatologic Science and Cosmetic Technology” This study found that extracts from Terminalia bellirica enhanced dermal papilla cell viability, inhibited androgen-related pathways, and stimulated hair regrowth in a mouse model, suggesting potential for treating androgenetic alopecia through multi-target mechanisms.
April 2025 in “Pharmacognosy Magazine” In this study, researchers found that Compound Baqian Danshen Liniment may improve vitiligo in mice by promoting melanocyte activity and reducing inflammation and oxidative stress.
27 citations
,
January 2000 in “Developmental Dynamics” This study reports that a new nude allele, nu(StL), encodes a truncated Whn transcription factor affecting T-cell development and keratin gene expression, with notable differences from the original Whn(nu) mutation.
75 citations
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April 2000 in “Developmental Dynamics” This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.
8 citations
,
July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
130 citations
,
September 1990 in “Journal of the American Academy of Dermatology” This study found that combining flutamide with an oral contraceptive significantly reduced hirsutism, acne, and seborrhea in patients after seven months, without significant side effects.
23 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical minoxidil and diazoxide induced significant hair regrowth in bald macaques, while a steroid 5 alpha-reductase inhibitor prevented baldness in preadolescent macaques.
20 citations
,
December 2019 in “International Journal of Molecular Sciences” This study found that preconditioning adipose-derived stem cells with HB-EGF enhanced their ability to promote hair growth in vivo by increasing their motility, paracrine effects, and survival.
16 citations
,
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.
2 citations
,
November 2024 in “International Journal of Pharmaceutics X” In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.
109 citations
,
June 2011 in “Molecular and Cellular Endocrinology” Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.
74 citations
,
April 2002 in “PubMed” This study found that the oral contraceptive containing drospirenone (EE/DRSP) was as effective as EE/CPA in reducing acne lesions, sebum production, and hair growth in women with acne.
70 citations
,
February 2016 in “EMBO reports” This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.
50 citations
,
February 2004 in “Genomics” This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
28 citations
,
July 2008 in “Developmental Biology” This study found that the loss of Smad4 in keratinocytes reduces Dsg4 expression via disrupted BMP signaling, contributing to hair follicle degeneration and alopecia.
24 citations
,
May 2019 in “PLOS genetics” This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.
19 citations
,
January 2009 in “International review of cell and molecular biology” This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.
1 citations
,
January 2024 CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
The researchers reported that PEG-FGF2 conjugates, particularly Compound 6, significantly enhanced stability, proliferation, migration, and wound healing activity compared to native FGF2, despite some reduction in bioactivity near crucial binding domains.
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.