Anti-Vitiligo Mechanisms of Traditional Chinese Medicine Compound Baqia Danshen Liniment: Network Pharmacology, Molecular Docking, and Animal Model Insights

    April 2025 in “ Pharmacognosy Magazine ”
    Jiaxin Wang, Juan Liu, Yahui Wang, Kailibinuer Abulaiti, Weili Sun, Maihesumu Aikemu, Muhebuli Abulizi
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    TLDR Compound Baqia Danshen Liniment may effectively treat vitiligo by improving skin and hair pigmentation and reducing inflammation.
    The study investigates the anti-vitiligo effects of the Traditional Chinese Medicine compound Baqia Danshen Liniment using network pharmacology, molecular docking, and animal models. The research identifies key active compounds and potential targets involved in the treatment of vitiligo. Molecular docking results suggest strong binding affinities between the active compounds and target proteins, indicating potential therapeutic effects. Animal model experiments further demonstrate the liniment's efficacy in promoting repigmentation and reducing depigmented areas. The findings support the potential of Baqia Danshen Liniment as an effective treatment for vitiligo, providing a scientific basis for its traditional use.
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