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Certain Dibenzo derivatives may help treat prostate cancer.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

Hair loss is a common side effect of hormone treatments for cancer.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Laser device increases hair density, safe for treating hair loss in men and women.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.