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Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride may cause long-lasting sexual side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Dermatologists are more accurate than general practitioners in diagnosing skin conditions, especially skin cancer.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.