August 2026 in “Cosmetics” This review assessed dermo-cosmetic treatments using prebiotics, probiotics, synbiotics, and other biotics for acne and scalp disorders, finding potential benefits, especially with multi-strain or synbiotic formulations, although challenges like formulation stability and the need for larger trials persist.
January 2025 in “Investigative and Clinical Urology” This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.
27 citations
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February 2017 in “Biomedicine & Pharmacotherapy” This study found that white wax and its extract may promote hair growth in a mouse model of androgenetic alopecia by inhibiting 5α-reductase activity and increasing cell proliferation, with efficacy surpassing finasteride.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
61 citations
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September 2010 in “Fitoterapia” This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.
June 2025 in “Jurnal Mandala Pharmacon Indonesia” In this study, researchers found that methanol extract from E. alba stem reduced the expression of the apoptosis marker gene Caspase-3 in T47D breast cancer cells, particularly at 100 ppm, achieving 1.859 times suppression compared to DMSO 2%.
21 citations
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May 2021 in “Materials & Design” This study developed a new multifunctional medical dressing using Bletilla striata polysaccharide and ethanol extract that demonstrated hemostatic, antibacterial, and significant wound healing effects, as evidenced by quicker healing rates and improved skin conditions in treated wounds compared to controls.
September 2017 in “World journal of Pharmacy and pharmaceutical sciences” In this study, researchers observed that a polyherbal ointment made from specific plant extracts significantly promoted hair growth in rats compared to ointments with single extracts, possibly due to the presence of flavonoids and tannins.
June 2026 in “Frontiers in Physiology” In this study, a topical cream containing 3% lactic acid ferment lysate (VHProbi ® MixP) was found to significantly reduce sebum, porphyrin levels, and pore size, while increasing hydration and improving skin texture in participants with oily skin over a 60-day period.
October 2025 in “Jurnal Medisains Kesehatan” This experimental study found that leaf extracts from Averrhoa bilimbi and Muntingia calabura significantly inhibited the growth of Staphylococcus aureus, with M. calabura demonstrating stronger antibacterial activity, suggesting potential for acne treatment.
8 citations
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July 2017 in “Biochemical and biophysical research communications” This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal shampoo enriched with pomegranate peel extract, reporting good cleansing ability, stable foam, scalp-friendly pH, and no irritation, suggesting it could be a safe, effective alternative for protecting hair from pollution-related damage.
January 2024 in “Future postharvest and food” This study reviewed the historical and current uses of frankincense, highlighting its potential antiviral, anti-inflammatory, and immunomodulatory effects, particularly noting some clinical evidence that suggests its use in treating COVID-19 symptoms, although more data is needed.
April 2017 in “Journal of Dermatological Science” In this study, both 2.5% benzoyl peroxide gel and 0.1% adapalene gel exhibited comedolytic effects on the spontaneous comedogenic rhino mouse model.
3 citations
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April 2016 in “Research and reports in urology” In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
This study observed that liposomes encapsulating minoxidil and PEP penetrate the skin at a slower rate but may reach deeper layers compared to a foam formulation.
April 2024 in “Natural Product Communications” This study identified that the pruning woods from Juniperus phoenicea and Juniperus thurifera could serve as renewable sources of bioactive natural products, with compounds like cedrol showing potent antitick and antifungal activities.
January 2025 in “Regenerative Biomaterials” In this study, a cerium-polypeptide hydrogel was found to effectively treat MRSA-infected wounds by promoting faster wound repair and reducing inflammation compared to a standard hydrogel.
January 2025 in “Faculty of 1000 Research Ltd” Plant-based treatments may help reduce BPH symptoms, but more research is needed.
October 2015 in “Elsevier eBooks” Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
17 citations
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April 2017 in “International Journal of Biological Macromolecules” This study found that alginate beads containing monoolein demonstrated promising potential for managing wet wounds by better absorbing excess exudate and delivering adenosine locally, favoring drug localization in damaged porcine skin compared to an aqueous solution without affecting skin viability.
April 2025 in “Jurnal Inovasi Bahan Lokal dan Pemberdayaan Masyarakat” This study found that variations in propylene glycol concentration in wax apple leaf extract hair tonic affected pH, specific gravity, and viscosity, aligning with SNI requirements.
3 citations
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June 2023 in “Journal of cosmetic dermatology” This study found that a topical cream containing CBD and EPA reduced signs of extrinsic skin aging, including wrinkle volume and skin elasticity, in clinical and laboratory settings.
1 citations
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January 2023 in “Chemical Engineering Journal” January 2023 in “Applied sciences” This study suggests that Equisetum debile extracts, particularly the ethyl acetate fraction, may offer natural cosmeceutical benefits for treating hyperpigmentation, delaying skin aging, and remediating hair loss due to androgenic alopecia.
34 citations
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January 2022 in “Molecules/Molecules online/Molecules annual” This review highlights the use of natural products in cosmetic-containing herbals for skin and hair care but reports no new clinical results, calling attention to their claimed curative properties and minimal side effects.
This study found that a polyherbal formulation of Trigonella foenum-graecum seeds and Butea monosperma flowers significantly promoted hair growth and reduced dihydrotestosterone levels in a chemotherapy-induced alopecia model.
2 citations
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January 2007 in “edoc (University of Basel)” This study identified Aquilaria sinensis and Piper cubeba as tropical plants with potential anti-androgenic and anti-estrogenic properties that could help prevent or alleviate benign prostatic hyperplasia and prostate cancer.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.