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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

Panax ginseng extract helps mice grow hair.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Adrenal disorders can cause lasting brain and behavior issues in children.

Hair loss requires customized treatments based on its various causes and types.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Topical 0.1% tacrolimus significantly improved ear infections in cats.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

The conclusion is that the best approach for treating Female Pattern Hair Loss is a combination of different treatments.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

Most hair loss in captive rhesus macaques is likely due to environmental and behavioral factors.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Certain electric currents can promote hair growth by activating specific cell pathways.

Behavior therapy and medications, especially clomipramine, can help reduce hair pulling in people with trichotillomania.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Male hormones worsen kidney transplant damage, but blocking them helps.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Skin infections in cats are more common than thought, often affect young cats with allergies, and need better treatments.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.