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Researchers created human hair follicles using a new method that could help treat hair loss.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

PEVs improve minoxidil skin penetration, increasing hair growth.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Finasteride effectively treats baldness but may cause sexual side effects.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Hair loss linked to higher heart disease risk in both men and women.

New treatments targeting specific genes show promise for treating keratin disorders.

Corkscrew hair may be a new sign for quickly diagnosing scalp fungus in black children.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.