22 citations
,
March 1994 in “Journal of Heredity” In this study, researchers identified a mutation in mice that causes hair loss and immune system issues, located on chromosome 18.
21 citations
,
September 1979 in “Archives of Otolaryngology-head & Neck Surgery” This article reviews the use of the Juri procedure for transferring hair to bald scalps, achieving satisfactory cosmetic results in all patients over two years, but reports no new clinical findings.
21 citations
,
March 2013 in “Cancer Epidemiology, Biomarkers & Prevention” This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.
21 citations
,
January 2000 in “Aesthetic Plastic Surgery” This study introduced a new classification method for male pattern baldness in Korean men, detailing six types that could guide hair restoration surgery and further research.
19 citations
,
December 2008 in “Medical Journal of Australia” This study found no significant association between the degree of male-pattern baldness and serum 25-hydroxyvitamin D levels in healthy middle-aged and older men.
17 citations
,
January 2016 in “American Journal of Epidemiology” This study suggests that any baldness, particularly moderate balding, is associated with a higher risk of fatal prostate cancer in men, supporting a possible link between hair loss and prostate cancer mechanisms.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” This study found that miniaturized hair follicles from pattern alopecia can regenerate rapidly when transplanted onto mice and may grow as well as or better than terminal hairs.
17 citations
,
May 2005 in “Hair transplant forum international” This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.
16 citations
,
January 2002 in “Dermatology” This study found that the parietal/occipital hair density ratio decreases significantly only when baldness is visibly present, making it no better than the Hamilton/Norwood scale for assessing baldness severity.
15 citations
,
January 2000 in “Japanese Heart Journal” This case report discusses a 45-year-old Japanese man who developed myocardial infarction while using 1% topical minoxidil for baldness, highlighting the need for caution in patients with cardiovascular disorders.
14 citations
,
April 2007 in “Journal of aging and health” This study observed that balding was associated with lower total body BMD in men and higher hip BMD in women, possibly due to estrogen use in the latter group.
10 citations
,
April 2009 in “Oncology Reports” This study found distinct skin surface changes, including faint mosaic melanoderma and atypical scaliness, on long-standing sun-exposed balding scalps that may be associated with actinic field carcinogenesis.
10 citations
,
April 2015 in “Netherlands Heart Journal” This study concluded that there is no association between male pattern baldness and the severity or presence of coronary artery disease as measured by Gensini and Rentrop scores.
10 citations
,
July 1981 in “Archives of Otolaryngology-head & Neck Surgery” This article reviews scalp flap surgery for hair restoration, emphasizing its ability to provide immediate and natural hair coverage compared to traditional hair transplantation, and reports no new clinical results.
10 citations
,
January 2005 in “Dermatology” This review discusses possible links between certain skin conditions and elevated coronary disease risk, but reports no new results and highlights methodological flaws in existing studies.
9 citations
,
December 1981 in “International Journal of Dermatology” The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.
9 citations
,
July 2018 in “Medicine” This meta-analysis suggests that individuals with vertex baldness may have a higher risk of prostate cancer, though overall baldness is not significantly associated with prostate cancer risk.
9 citations
,
November 1993 in “Journal of The American Academy of Dermatology” Some men can have female pattern baldness without hormonal abnormalities or signs of feminization.
8 citations
,
October 2008 in “Medical hypotheses” This article introduces a new theory on male pattern baldness, attributing it to scalp pressure affecting hair follicles, and suggests it could revolutionize understanding and treatment; no clinical results are presented.
8 citations
,
April 2001 in “Dermatologic Surgery” This proposal presents a standardized system for naming areas of the balding scalp to improve communication among hair restoration professionals, defining major regions and introducing new landmarks.
8 citations
,
February 1982 in “Plastic & Reconstructive Surgery” This article discusses scalp reduction as a technique in male pattern baldness, highlighting its potential to enhance hair transplantation outcomes, but reports no new clinical results.
7 citations
,
October 2017 in “The Prostate” This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.
7 citations
,
January 2016 in “British Journal of Cancer” This study found that certain male pattern baldness subtypes at age 45 are associated with an increased risk of developing colorectal neoplasia.
7 citations
,
October 2008 in “Nature Genetics” Two key genetic areas linked to male-pattern baldness were identified.
6 citations
,
December 2013 in “Medical Journal of Australia” Bald men are not more virile and may have fewer sexual partners.
6 citations
,
January 2016 in “International Journal of Andrology” In this study, researchers found an inverse association between baldness and testicular cancer, suggesting androgen activity may influence cancer risk.
6 citations
,
September 2020 in “Journal of The American Academy of Dermatology” This letter discusses how severe baldness in men is associated with higher risk of severe COVID-19, and highlights research suggesting antiandrogen medications may improve outcomes.
5 citations
,
February 2019 in “PloS one” This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.
5 citations
,
January 1985 in “Facial Plastic Surgery” Flap surgery is effective for treating male baldness, offering immediate results with dense hair growth.
5 citations
,
August 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified over 250 new genetic loci linked to severe male pattern baldness, and developed a prediction algorithm that could accurately differentiate between those with severe and no hair loss.