20 citations
,
January 2014 in “International Journal of Trichology” This study found that early onset androgenetic alopecia in young Asian Indian Gujarati men is independently associated with an increased risk of coronary artery disease.
2152 citations
,
November 2013 in “Urologia Internationalis” This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.
26 citations
,
January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
24 citations
,
January 2013 in “Indian Dermatology Online Journal” This study found that males with androgenetic alopecia had a higher risk of coronary artery disease, with significant differences in several lipid and blood pressure markers compared to controls.
42 citations
,
January 2011 in “European Journal of Dermatology” In this study, higher scores of HOMA-IR and FIRI suggested that male patients with early-onset androgenetic alopecia may have insulin resistance, although no significant differences in metabolic syndrome were found compared to controls.
38 citations
,
February 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that patients with severe vertex pattern androgenetic alopecia had significantly higher carotid intima-media thickness, suggesting an increased risk of subclinical atherosclerosis compared to other alopecia patterns and healthy controls.
34 citations
,
August 2007 in “PubMed” This study found a strong association between androgenetic alopecia and hypertension in Caucasian men, independent of age.
72 citations
,
January 2007 in “Dermatology” This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.
193 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that the prevalence of androgenetic alopecia increases with age among both men and women in Maryborough, Australia, with 57% of women and 73.5% of men aged 80 and over affected.
37 citations
,
January 2005 in “Dermatology Online Journal” In this study, researchers observed a significant association between female androgenetic alopecia and coronary artery disease in women under 55, supporting a link similar to that seen in men.
52 citations
,
April 2004 in “Journal of The American Academy of Dermatology” This article proposes three mechanisms by which dihydrotestosterone may contribute to baldness but reports no new research findings.
56 citations
,
June 2001 in “European journal of cardiovascular prevention & rehabilitation” This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.
370 citations
,
September 1999 in “The New England Journal of Medicine” This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.
34 citations
,
March 1999 in “Journal of The European Academy of Dermatology and Venereology” This study found significant differences in serum lipoprotein (a) and triglyceride levels between men with androgenetic alopecia and those with normal hair, suggesting a need for dermatologists to monitor lipid profiles in these patients.
581 citations
,
October 1998 in “Journal of The American Academy of Dermatology” In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.
227 citations
,
January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.