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Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Finasteride improves chronic pelvic pain, saw palmetto doesn't.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hair loss in men treated best with early medication or transplant, new treatments researched.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.