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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Removing part of the vitamin D receptor stops vitamin D from working properly.

FoxN1 overexpression in young mice harms immune cell and skin development.

Certain flavonoids help grow back colored hair after skin injury.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

XEDAR triggers a specific signaling pathway in cells.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Activin B helps start and grow hair follicles in mice.

A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

A20 protein is crucial for normal skin and hair development.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.

A new mutation in the K6b gene caused a girl's late-appearing nail condition.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Deleting part of a gene in mice causes wavy hair and high pup loss.