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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Removing part of the vitamin D receptor stops vitamin D from working properly.

FoxN1 overexpression in young mice harms immune cell and skin development.

Certain flavonoids help grow back colored hair after skin injury.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

XEDAR triggers a specific signaling pathway in cells.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Activin B helps start and grow hair follicles in mice.

A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

A20 protein is crucial for normal skin and hair development.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.

A new mutation in the K6b gene caused a girl's late-appearing nail condition.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Clim proteins are essential for maintaining healthy corneas and hair follicles.