This study found that 20% of children initially diagnosed with premature pubarche were later identified with different clinical conditions during follow-up, highlighting the need for careful differential diagnosis over time.
May 2005 in “Hair transplant forum international” This case report documents a 28-year-old woman who experienced complete scalp hair loss, which began a year earlier with patchy baldness and progressed to loss of eyebrow, axillary, and pubic hair.
October 1988 in “Pediatric research” In this study, researchers observed that the sequence of maturity markers in normal boys showed specific time lags, with some markers appearing before and others after spermarche.
126 citations
,
January 1987 in “Journal of The American Academy of Dermatology” This article reviews the classification of hair shaft abnormalities, outlining their diagnostic features, but does not present new research findings.
12 citations
,
March 1981 in “International Journal of Dermatology” This case study reports that selenium shampoo, bacterial infection with trichomycosis axillaris, and possibly strongyloides larvae may have contributed to acquired hair shaft abnormalities resembling trichorrhexis nodosa in two patients.
This study highlights the complexity of diagnosing scalp fungal infections, emphasizing how clinical evaluation, trichoscopy, and cultural samples are essential in distinguishing tinea capitis from similar conditions like piedra, seborrheic dermatitis, and psoriasis, due to overlapping symptoms like scaling and hair changes.
August 2021 in “BMJ Case Reports” This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.
June 2014 in “Zagazig Journal of Pharmaceutical Sciences/Zagazig Journal of Pharmaceutical Science” This study reports that using ascorbic acid or orlistat can significantly inhibit the metabolism of testosterone esters into malodorous metabolites by axillary bacteria, suggesting potential new deodorant applications.
48 citations
,
April 1995 in “PubMed” This study found that dermal papilla cells from beard and axillary hair follicles can produce androgen-dependent factors that stimulate proliferation in adjacent follicular epithelial cells under testosterone influence.
36 citations
,
August 2011 in “Experimental Dermatology” In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.
5 citations
,
February 2016 in “Sultan Qaboos University medical journal” This case report describes a patient with a severe pruritic rash and hair loss in both axillary regions, with no fluorescence under a Wood's lamp and hair follicle-centred papules observed through dermoscopy.
3 citations
,
May 2023 in “PLoS ONE” This study found that while both professional and home-use lasers effectively reduced axillary hair, the professional Diode laser was significantly more effective, achieving 85-88% reduction compared to 46-52% with the home-use laser, which still offers some safety for users.
4 citations
,
July 2006 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that testosterone significantly stimulated the proliferation of outer root sheath cells when co-cultured with beard or axillary dermal papilla cells, but not with cells from occipital scalp hair follicles.
January 2020 in “Research Square (Research Square)” In this study, Irish adults with severe obesity who had cervical or axillary skin tags showed higher systolic blood pressure, higher HbA1c levels, and more diabetes and hypertension, suggesting an increased vascular risk.
2 citations
,
January 2022 in “International journal of trichology” This case report details a rare instance of eruptive vellus hair cysts in a 12-year-old male, highlighting its atypical morphology and axillary distribution, which has not been previously documented.
June 2025 in “V F Snegirev Archives of Obstetrics and Gynecology” In this case study, a six-year-old girl was diagnosed with isolated adrenarche, linked to premature adrenal maturation, with increased dehydroepiandrosterone sulfate and axillary and pubic hair growth, and will require long-term monitoring due to increased risks of conditions like polycystic ovary syndrome and cardiovascular diseases.
June 2026 in “Lasers in Medical Science” This randomized trial found that diode laser achieved more favorable long-term hair removal outcomes but induced more discomfort and transient adverse effects compared to intense pulsed light in women with Fitzpatrick skin types I-IV.
49 citations
,
March 2004 in “Journal of Investigative Dermatology” This study found that the hHa7 gene in hair follicle trichocytes is the first identified to have its expression directly regulated by androgens, suggesting it as a marker for androgen action on hair follicles.
49 citations
,
September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.
11 citations
,
January 1987 in “Electrophoresis” This study found that keratin phenotypes were consistent across different types of hair from the same individual, allowing for successful keratin typing following ABH blood group determination.
5 citations
,
January 2010 in “The anatomical record” This study assessed hair whorl characteristics in domestic dogs and found that simple whorls predominate, with tufted whorls more common in specific regions like elbows and chests, influenced by factors such as coat traits and source.
1 citations
,
October 2023 in “European Journal of Dermatology” In this study, combining hair transplantation with platelet-rich plasma was found to be more effective than hair transplantation alone in reducing hair loss, improving hair regeneration, and decreasing skin lesions in patients with androgenic alopecia.
1 citations
,
August 2015 in “AACE Clinical Case Reports” This case report identifies a novel AR gene mutation in an adolescent with primary amenorrhea, suggesting that CAIS should be considered when evaluating patients with a female phenotype and breast development.
June 2026 in “Skin Appendage Disorders” This study suggests that pili annulati is likely more common than traditionally thought, highlighting the importance of recognizing its characteristic clinical and trichoscopic features for accurate diagnosis.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This review discusses microneedling radiofrequency in cosmetic dermatology, particularly for skin texture improvement and various conditions, and reports no new clinical results.
January 2026 in “Forum Dermatologicum” This study reviewed cases of Graham–Little-Piccardi–Lassueur syndrome and found that topical treatments were generally ineffective, while systemic therapies like prednisone, hydroxychloroquine, and isotretinoin led to partial hair regrowth and disease stabilization, highlighting the importance of early diagnosis and systemic therapy to improve outcomes.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
February 2020 in “Research Square (Research Square)” In this study, skin tags in Irish adults with morbid obesity were associated with higher blood pressure, higher HbA1c levels, and a greater prevalence of diabetes and hypertension, suggesting increased cardiovascular risk.
April 2017 in “Turkish Journal of Pediatric Disease” This study found that 20% of children initially diagnosed with premature pubarche were later identified with other conditions like central puberty precox or congenital adrenal hyperplasia during follow-up, emphasizing the importance of ongoing differential diagnosis.
July 2013 in “Indian Journal of Dentistry” This report describes a rare case of Graham-Little–Piccardi–Lassueur syndrome in a 46-year-old male, highlighting its typical features such as scarring alopecia and lichenoid follicular eruptions.