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Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

Minoxidil helps hair growth by activating the β-catenin pathway.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Skin has specialized touch receptors that can tell different sensations apart.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

TRH stimulates human hair growth and extends the hair growth phase.

Human hair follicles can regenerate after removal, but with low success rate.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

New genes and pathways are important for testosterone production and male sexual development.

Androgens slow hair growth by altering Wnt signaling in balding cells.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Some breast cancer chemotherapy can cause permanent hair loss.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.