Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.

This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.

This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.

This review discusses alopecia areata as a model for studying tissue-directed autoimmune diseases and reports no new clinical findings.

This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.

This source discusses autoimmune disorders, noting that the presence of autoantibodies can precede disease development, especially in genetically predisposed individuals, with various triggers like vitamin D deficiency and UV exposure potentially influencing onset and severity.

Enhancing regulatory T cells may help treat autoimmune diseases like alopecia areata.

BTNL2 helps protect hair follicles from immune attacks.

This case report describes a rare association where herpes zoster infection may have triggered the first attack of NMOSD with systemic vasculitis in a patient, suggesting potential overlaps in immunopathogenesis.

This review discusses the pathogenesis of alopecia areata, highlighting the role of immune privilege collapse in hair follicles but reports no clinical results.

This article discusses the potential role of nutrition in managing vitiligo and reports no new research results, highlighting the need for further investigation.

This article reviews current and emerging treatments for alopecia areata, emphasizing the need for biomarker-driven patient stratification to optimize therapeutic strategies and reduce potential side effects; it reports no new clinical findings.

This literature review examines the complexities of childhood alopecia areata, focusing on its forms, gene expression, and causes, providing a comprehensive analysis of this autoimmune disorder.

This abstract discusses alopecia areata, highlighting its complex autoimmune pathogenesis involving immune cells and signaling molecules, and underscores the importance of accurate diagnosis and tailored management strategies, noting the need for further research to improve treatments.

In this case report, a nearly 12-year-old boy with alopecia universalis and atopic dermatitis experienced full hair regrowth and improved dermatitis following treatment with upadacitinib, a JAK 1 inhibitor, showing notable positive effects on his psychological well-being and family.

This article reviews the role of vitamin D in regulating immune responses related to autoimmune diseases like alopecia areata, but it presents no new clinical findings.

This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.

This source highlights that the incidence of alopecia areata is increasing among children, and while corticosteroids and Janus kinase inhibitors show potential effectiveness and safety, they remain unapproved by the FDA for pediatric use.

This review covers the epidemiology, risk factors, and diagnosis of alopecia, highlighting existing treatments like finasteride and minoxidil but focusing on new strategies without providing clinical results.

This review provides an overview of genetics, causes, and treatment options for alopecia areata but reports no new clinical results and emphasizes the importance of support for those affected.

In this study, researchers explored the immunological mechanisms involved in alopecia areata and suggested that targeting immune responses, particularly using JAK inhibitors and other immunomodulatory drugs, could help achieve stable remission and improve patients' quality of life.

This review explores the autoimmune hypothesis of alopecia areata and the possible genetic and melanogenesis-associated autoantigens, but reports no new clinical findings.

This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.

This study utilized targeted genomic sequencing and whole exome sequencing to identify novel common and rare genetic variants in Alopecia Areata, revealing potential mechanisms contributing to disease susceptibility.

This review discusses the challenges in identifying specific hair follicle antigens involved in initiating alopecia areata and highlights the need for further research to understand its etiopathogenesis, reporting no new results.

This study found that Egyptian patients with alopecia areata had a significant presence of sensorineural hearing loss compared to controls, correlated with the severity, duration, and recurrence of the disease.

This article reviews treatments for alopecia areata, including corticosteroids and other immunomodulators, and reports no new experimental findings.

This abstract provides background information on alopecia areata, describing it as an autoimmune condition leading to non-scarring, patchy hair loss but does not report specific study results.

Trichohyalin in hair can trigger immune attacks in alopecia areata.

This article discusses the challenges in diagnosing and treating autoimmune diseases, emphasizing the need for regenerative medicine approaches to address the root causes rather than just suppressing symptoms.