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Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Hair follicle sampling is a feasible method to measure FMRP and FMR1 mRNA levels in children.

Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

The document explains how to identify different hair problems using a microscope.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.