January 2025 in “International Journal of Gynaecology Research” This study found that serum cystatin C levels may be elevated in adolescent females with PCOS, suggesting it could serve as a predictive marker for metabolic and cardiovascular issues independent of renal function.
In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.
May 2021 in “Austin journal of pharmacology and therapeutics” This study explores the medicinal and environmental applications of Physalis species, highlighting the wound healing properties of Physalis angulata L. and the antibacterial and antitumor activities of its fruit extracts.
April 2021 in “Journal of evolution of medical and dental sciences” This study found that bioavailable testosterone and the free androgen index were significantly associated with various clinical and biochemical features of PCOS, including hirsutism, showing higher levels in PCOS patients compared to controls.
November 2020 in “Journal of Pharmaceutical Sciences” This study suggests a decision tree using in vitro metabolic clearance to identify early drug candidates likely to experience nonlinear pharmacokinetics due to intestinal CYP3A-related metabolism.
June 2020 in “Journal of Investigative Dermatology” This study reported that a treatment serum containing ingredient blends with panthenol, licorice extract, and red clover extract significantly improved hair volume, scalp coverage, and reduced hair breakage over 6 months in individuals with thinning or damaged hair.
June 2017 in “Journal of The American Academy of Dermatology” Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
June 2017 in “Journal of The American Academy of Dermatology” Teriflunomide often causes mild to moderate hair thinning and loss in MS patients, which usually improves with or without treatment.
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
May 2017 in “Journal of The American Academy of Dermatology” 595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.
September 2024 in “Drugs & Therapy Perspectives” In this study, ritlecitinib, an oral medication approved for adolescents and adults, significantly reduced scalp hair loss and promoted eyebrow and eyelash regrowth in severe alopecia areata patients, with benefits sustained over 48 weeks and generally well-tolerated minor side effects.
June 2024 in “International journal of nanomedicine” This study highlights that current research efforts to deliver anti-acne drugs to hair follicles have primarily targeted healthy follicles, overlooking the distinct characteristics of pathologically clogged follicles in acne vulgaris.
October 2023 in “Urologie in der Praxis” This article reviews the diagnostics and medical transition options for adults with gender incongruence, reports no new clinical results, and highlights the importance of primary care knowledge in managing these patients.
This overview discusses the condition and treatments for alopecia areata, highlighting that the JAK inhibitor baricitinib, recently approved for severe cases, shows unprecedented effectiveness but raises cost and risk debates regarding treatment of this primarily cosmetic autoimmune disorder.
January 2021 in “Online Publication Service of Würzburg University (Würzburg University)” This study examines the use of diphenylcyclopropenone in treating alopecia areata patients at the University Hospital Würzburg and investigates how the treatment affects patients' quality of life.
February 2020 in “Diabetologie Und Stoffwechsel” This article reviews treatment strategies for polycystic ovary syndrome, specifically recommending letrozole for infertility, while also discussing lifestyle changes and other potential therapies, and reports no new research findings.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting all three Tet genes in mice led to shorter hair shafts and altered hair types, with associated changes in gene expression and DNA hydroxymethylation.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
April 2019 in “Journal of Investigative Dermatology” This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.
January 2018 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that donor age and culture medium significantly impact the quality of human full-thickness skin models, with implications for their use as animal model alternatives in research.
July 2017 in “Clin-Alert” Different medications can cause serious side effects in some people.
January 2017 in “Qucosa (Saxon State and University Library Dresden)” This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.
November 2016 in “Der Hautarzt” This article presents case reports of three women with hair thinning primarily on the top of the head, suggesting a pattern consistent with female-type androgenetic alopecia, though this is not diagnostic.
August 2016 in “PolyPublie (École Polytechnique de Montréal)” This study observed early cardiac effects in young minipigs following high-dose doxorubicin chemotherapy, with a decrease in heart function and changes in cardiac MRI measurements compared to controls.
January 2016 in “Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)” FDG PET/CT can improve cancer treatment plans in dogs.
March 2015 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This article discusses testosterone production in the human body and its effects on muscle mass, bone density, metabolism, and skin, but reports no new findings.
October 2014 in “Aktuelle Dermatologie” This study reports that elderly men with baldness and comorbid conditions experienced persistent scalp erosions following topical treatment with imiquimod or diclofenac, suggesting alternative therapies should be considered for this group.