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Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.

Adrenal disorders can cause lasting brain and behavior issues in children.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

Hair thinning and loss in a girl with a rare metabolic disorder was linked to her condition.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Many skin patients also have mental health issues, and doctors should treat both together.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.