research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
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research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
research Germline Mutation in ATR in Autosomal-Dominant Oropharyngeal Cancer Syndrome
A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Cosmeceutical Therapy: Addressing the Effects of UVR Photoaging on the Skin’s Circadian Rhythm
Natural skincare products may help reduce sun damage and support the skin's daily cycle.
research ATP-Competitive mTOR Kinase Inhibitors Delay Plant Growth by Triggering Early Differentiation of Meristematic Cells Without Developmental Patterning Change
Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
research Look at Your Hair the Way You Look at Your Face: Concept of Total Facial Skin and Hair Care
Take care of your hair as much as your face for a youthful look.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Lamins in Development, Tissue Maintenance, and Stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies
Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
research Oxidative Stress in Aging of Hair
Oxidative stress contributes to hair graying and loss as we age.
research Hair Follicle Stem Cell Fate Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation
Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control
TRH stimulates human hair growth and extends the hair growth phase.
research Radiation-Induced Alopecia
A man experienced hair loss from radiotherapy, which can be temporary or permanent depending on radiation dose, with potential treatments available.
research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury
MG53 helps reduce skin damage caused by nitrogen mustard.
research Caffeine’s Mechanisms of Action and Its Cosmetic Use
Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Skin Manifestations in Primary Immunodeficient Children
Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Cutaneous Side Effects of Chemotherapy and Radiotherapy
Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
research Cutaneous Signals of Immune System Disease
Skin issues can indicate immune system problems.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study
Artemis protein may help control hair growth and health by influencing cell processes.