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    Glossary Ataxia Telangiectasia and Rad3-related protein

    enzyme ATR detects DNA damage and activates repair mechanisms

    Ataxia Telangiectasia and Rad3-related protein, commonly known as ATR, is a crucial enzyme involved in the cellular response to DNA damage. It helps maintain genomic stability by detecting DNA damage and activating repair pathways, thus preventing mutations that could lead to diseases like cancer.

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    Research 30 of 363

    1. Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin International journal of molecular sciences · 2024
    2. Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes Iranian journal of pharmaceutical research · 2025 · 1 citations
    3. Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss Cell Stem Cell · 2007 · 688 citations
    4. Aging Skin: A Window to the Body CRC Press eBooks · 2016 · 1 citations
    5. Oxidative stress in ageing of hair International Journal of Trichology · 2009 · 126 citations
    6. Removing all obstacles: A critical role for p53 in promoting tissue renewal Cell Cycle · 2010 · 30 citations
    7. Progeroide Syndrome Die Dermatologie · 2023 · 2 citations
    8. Germline Mutation in ATR in Autosomal- Dominant Oropharyngeal Cancer Syndrome The American Journal of Human Genetics · 2012 · 71 citations
    9. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression Journal of Investigative Dermatology · 2007 · 141 citations
    10. MG53 Mitigates Nitrogen Mustard-Induced Skin Injury Cells · 2023 · 3 citations
    11. A Multifaceted View on Ageing of the Hair and Scalp Cosmetics · 2025 · 2 citations
    12. ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change Journal of experimental botany · 2013 · 161 citations
    13. ROR2 regulates self-renewal and maintenance of hair follicle stem cells Nature Communications · 2022 · 16 citations
    14. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    15. Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage PLOS ONE · 2013 · 30 citations
    16. Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation Stem cells · 2017 · 13 citations
    17. Look at Your Hair the Way You Look at Your Face: Concept of Total Facial Skin and Hair Care Skin Appendage Disorders · 2020 · 7 citations
    18. Cellular senescence and polycystic ovary syndrome: mechanisms and therapeutic strategies from a new perspective Annals of Medicine · 2025 · 2 citations
    19. Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche Cell stem cell · 2011 · 695 citations
    20. Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin’s Circadian Rhythm International journal of molecular sciences · 2022 · 6 citations
    21. Chemotherapy-Induced Alopecia Beyond Cytotoxicity: Hair Follicle Immune Privilege Collapse and JAK-STAT Signaling International Journal of Molecular Sciences · 2026
    22. Coffea arabica: An Emerging Active Ingredient in Dermato-Cosmetic Applications Pharmaceuticals · 2025 · 5 citations
    23. Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp Scientific reports · 2020 · 14 citations
    24. Skin Manifestations in Primary Immunodeficient Children Pediatric Dermatology · 2011 · 57 citations
    25. Abstracts from the 4th Annual Student Medical Summit BMC Proceedings · 2021 · 1 citations
    26. Replicative stress, stem cells and aging Mechanisms of Ageing and Development · 2008 · 70 citations
    27. Cutaneous signals of immune system disease Current problems in dermatology · 1991
    28. The Clinical Presentation of Systemic Lupus Erythematosus Elsevier eBooks · 2011 · 33 citations
    29. Cerebellar Medulloblastoma: Treatment by Irradiation of the Whole Central Nervous System Acta Radiologica · 1953 · 1 citations
    30. Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation Pigment Cell & Melanoma Research · 2011 · 240 citations