11 citations
,
January 2020 in “BMC pediatrics” This case report identified two new SLC39A4 mutations in twin patients with acrodermatitis enteropathica, suggesting that different mutations in this gene may lead to varying clinical manifestations of the disorder.
273 citations
,
May 2017 in “The Lancet” This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
1 citations
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June 2019 in “Journal of Cutaneous Immunology and Allergy” This report describes two cases where topical squaric acid dibutylester application in alopecia totalis patients led to severe pustular lesions, necessitating systemic prednisolone treatment.
September 2024 in “Vietnam Journal of Biotechnology” This study found that astaxanthin effectively protected human dermal papillae cells from oxidative stress induced by hydrogen peroxide, reducing the percentage of cells expressing a stress marker significantly, suggesting potential benefits for hair loss treatment related to reactive oxygen species.
1 citations
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February 2025 in “Archives of Dermatological Research” Using Excimer light with topical steroids is the most effective treatment for alopecia areata.
157 citations
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October 2003 in “Development” This study found that different stabilizing mutations in Aux/IAA proteins affect root hair development in Arabidopsis by disrupting the auxin response and suggest a model where the relative abundance of these proteins determines root hair initiation.
This study describes an adaptive hair extension method designed to improve comfort, durability, and aesthetics, based on analysis of hypothetical client profiles and their biomechanical tolerance.
22 citations
,
July 2024 in “Frontiers in Oncology” This study found that FLASH radiation within a Spread-out Bragg Peak retained its normal tissue-sparing effect compared to conventional radiation, with a 40% reduction in acute skin damage and an 18% reduction in fibrotic development in mice.
6 citations
,
October 2016 in “Pediatric Dermatology” This case report describes a unique instance of a 6-year-old girl developing angioedema after treatment with squaric acid dibutylester for alopecia areata.
20 citations
,
May 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case report, etanercept was observed to effectively resolve symptoms of refractory acrodermatitis continua suppurativa Hallopeau after previous treatments had limited success.
April 2023 in “Journal of Investigative Dermatology” This study reports that improvements to the EczemaNet pipeline, incorporating pixel-level segmentation and data augmentation, enhanced the reliability and interpretability of assessing atopic dermatitis severity from digital images.
10 citations
,
June 2019 in “Dermatologic therapy” In this study, treatment with DPCP alone was more effective for hair regrowth and presented fewer side effects in chronic extensive alopecia areata compared to combination therapy with DPCP and anthralin.
42 citations
,
August 1987 in “Archives of Dermatology” In this study, 28.5% of patients with extensive alopecia areata had complete hair regrowth during treatment with squaric acid dibutylester, with outcomes linked to shorter alopecia duration and prompt dermatitis development.
5 citations
,
January 2018 in “Skin Pharmacology and Physiology” This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.
1 citations
,
January 2013 April 2018 in “Journal of Investigative Dermatology” Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
35 citations
,
March 2010 in “Journal of Dermatological Science” Ebastine may help regrow hair in alopecia areata patients.
43 citations
,
July 1994 in “Journal of Cell Science” This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.
January 2024 in “JEADV clinical practice” This article reviews how SALT scores are used in clinical trials for alopecia areata and provides patient images to help clinicians understand and apply these scores in practice; it reports no new clinical results.
July 2024 in “Journal of Investigative Dermatology” This study suggests that macrophages, especially CD206+ subsets, play a key role in hair growth induced by squaric acid dibutyl ester, a therapy used for alopecia areata.
23 citations
,
June 2010 in “Journal of Investigative Dermatology” This study found that the hair interior defect in AKR/J mice is linked to a mutation in the Soat1 gene, which disrupts SOAT1 protein expression and affects lipid metabolism critical for normal hair formation.
8 citations
,
January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
2 citations
,
October 2012 in “Experimental Dermatology” This study found that, despite the unchanged total level of 18-MEA, deletion of the Sox21 gene disrupts its attachment to the hair cuticle, increases cholesterol sulphate levels, and differentially affects ceramide composition.
1 citations
,
March 2023 in “SKIN The Journal of Cutaneous Medicine” 21 citations
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September 2013 in “Current medicinal chemistry” This study found that co-drugs synthesized from hydroquinone and tranexamic acid improved skin targeting and deposition, with reduced irritation and enhanced efficacy for treating hyperpigmentation.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
4 citations
,
March 2023 in “IP International Journal of Comprehensive and Advanced Pharmacology” This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that rare damaging variants in the KRT82 gene, which affect hair shaft integrity, may contribute to the risk of alopecia areata.
3 citations
,
January 1989 in “Journal of Japan Oil Chemists Society” This study examined the effects of six surfactants on hair and scalp, finding varying irritation levels and impacts on protein denaturation and scalp turnover time, with AMT suggested as a good detergent.
15 citations
,
September 2018 in “Dermatologic therapy” In this study, the use of two emollients significantly reduced itching severity in individuals with xerotic eczema, starting 30 minutes post-application, and improved skin moisture and lipid content over 14 days, while demonstrating good tolerance with few adverse events.