January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
8 citations
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July 2002 in “X-Ray Spectrometry” In this study, researchers found a correlation between x-ray patterns and the element composition of human hair, with certain metal roles in the hair matrix considered.
1 citations
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November 2008 in “Acta crystallographica” This study reports the crystallization of the human androgen receptor's ligand-binding domain with nonsteroidal ligands, which may aid in understanding the differences in binding compared to steroidal ligands.
7 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This review discusses the confusion and misuse of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea, highlighting their plant origins, uses, and toxicities, without providing new clinical results.
15 citations
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January 2010 in “Reproduction, Fertility and Development” This study found that Han Chinese women carrying the rs6152A allele had a significantly higher risk of developing polycystic ovary syndrome compared to those with the rs6152GG genotype.
April 2023 in “Journal of Investigative Dermatology” Periodontitis may increase the risk of developing alopecia areata.
46 citations
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June 2015 in “Journal of Investigative Dermatology” This study found that androgen receptor activation in adult mouse skin reduces β-catenin-induced hair follicle growth and sebaceous gland conversion, highlighting its role in stem cell fate decisions.
May 2026 in “Journal of Medicinal Chemistry” In this study, the authors developed a novel PROTAC named dAR-6–1, which demonstrated superior hair regeneration in an AGA mouse model compared to minoxidil, highlighting its promise as a therapy due to potent AR degradation and excellent skin permeability.
May 2015 in “The Journal of Dermatology” This article is a letter to the editor regarding a case of alopecia areata with polymyalgia rheumatica and does not report new clinical results.
183 citations
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July 2000 in “American Journal of Botany” In this study, wild-type Arabidopsis thaliana demonstrated increased phosphorus acquisition and growth compared to root hair mutants under low-phosphorus conditions.
January 2012 in “Chinese Journal of Aesthetic Medicine” This study found that in hair follicles, androgen receptor expression is stronger in the hair loss and transitional areas compared to the occipital region, suggesting a role in male pattern baldness.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that local pollution from settlements and livestock farms in Turkey's Araz River basin is observed, but ecological stability is restored within 18-20 km of the flow, unlike more severe pollution in the Armenian section.
This study found that cell strains overexpressing the androgen receptor proliferated better in low or no DHT conditions and translocated AR more efficiently than control strains.
March 2026 in “Food Science & Nutrition” In this study, high-dose Arachis hypogaea root extract significantly reduced prostate weight and markers of glandular hyperplasia in testosterone-induced BPH in mice, with associated changes in inflammatory gene expression and beneficial shifts in gut microbiota.
14 citations
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December 2016 in “Sexual Medicine” This study identified differences in adverse symptoms among patients with post-finasteride syndrome based on short and long androgen receptor gene polymorphisms.
66 citations
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January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
20 citations
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April 2000 in “Experimental dermatology” This study observed that overexpression of the enzyme ODC in transgenic mice caused hair loss and skin changes similar to human papular atrichia, suggesting that ODC might be involved in a critical hair follicle function pathway.
20 citations
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May 2000 in “Journal of The American Academy of Dermatology” This report suggests that orf infections in Brussels often occur after the Islamic Feast of Sacrifice due to the ritual sheep sacrifice, affecting both men and women handling the animals.
January 2023 in “Intisari Sains Medis” This study found a significant relationship between andropause and androgenic alopecia among civil servants at the Badung Regency Government Center.
In this study, researchers optimized the soft drug AR antagonist 14-P1 to create candidate 39, which demonstrated effective AR antagonism and safety in a hair-growth mouse model, showing similar efficacy to pyrilutamide but with quicker onset and a lower risk of systemic toxicity.
December 2025 in “Clinical & Experimental Dermatology and Therapies” This study reported that Cosmerna ARI significantly improved androgenetic alopecia in Europeans over a 6-month period compared to a placebo, according to a double-blind, randomized, placebo-controlled clinical trial.
20 citations
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October 2005 in “Archives of Dermatological Research” 36 citations
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July 2022 in “Journal of Medicinal Chemistry” This review discusses various compounds targeting the androgen receptor, including recent developments in heterobifunctional degraders for prostate cancer treatment, but reports no new clinical results.
22 citations
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January 2009 in “Medical mycology” In this case report, researchers identified Arthroderma vanbreuseghemii as the cause of a familial fungal infection, which was successfully treated with itraconazole and topical terbinafine cream.
This study reports that the newly optimized AR antagonist 39 demonstrated effective hair growth and safety in a mouse model of androgenetic alopecia, showing comparable efficacy to pyrilutamide with faster response and favorable pharmacokinetics, due to innovative structural design and dual metabolic inactivation strategy.
September 2025 in “Blood Advances” This study found that targeting androgen receptors with prostate cancer drugs ARN509 and finasteride induced remission and increased survival in a leukemia mouse model, suggesting a potential new treatment approach for acute myeloid leukemia.
4 citations
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January 2017 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Gagamhwajung-hwan may effectively treat severe alopecia areata.
December 2025 in “Jurnal Ilmiah Kesehatan (JIKA)” This study found that a 15% concentration of Wilalondahi bark extract gel significantly improved wound healing and reduced inflammation in mice, with wounds completely healed by day 9, demonstrating comparable effectiveness to the positive control.
February 2025 in “Journal of Pharmaceutical and Health Research” This study examined the cytotoxic effects of arumanis mango rind extract and its fractions on T47D breast cancer cells, with results showing that ethanol extract and ethyl acetate fraction exhibited significant potential in reducing cell viability, similar to the effects of doxorubicin.
76 citations
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April 2005 in “Cancer Epidemiology, Biomarkers & Prevention” This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.