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Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Hair transplant surgery is the most effective, safe, and satisfying treatment for hair loss.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Hormones control reproduction and are crucial for body balance.

Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.

Hidden fungal infections might cause heart disease and clogged arteries.

Stopping forehead irritation and using hydrocortisone helped a man's skin, Martinique has lower melanoma rates, a man had an allergy to a specific antifungal, another had unexplained cysts, certain drugs can cause skin reactions without always being interrelated, a link between Fanconi anemia and a skin condition was suggested, high levels of a certain protein may play a role in a type of psoriasis, and there's a need to study the connection between scalp pain and hair loss.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Skin aging reflects overall body aging and can indicate internal health conditions.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.

Long COVID causes various long-term health issues and needs better awareness and treatment.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

PRP treatment can safely improve short-term vision in acute NAION patients.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

The skin microbiome helps heal wounds and can be targeted to improve healing.

More research is needed to find effective treatments for sickle cell disease-related priapism.

Nearly half of the classification tools in the National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries might not effectively guide management for general practitioners.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

Zolpidem shows up in hair from the top back of the head after one dose and fades over time, suggesting it gets into hair through blood and sweat.

Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.