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New method makes important drug ingredients more easily without needing extra purification steps.

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

Human skin can make serotonin and melatonin, which help protect and maintain it.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

The new palladium catalyst is effective and reusable for making pharmaceutical ingredients.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Wrightia tinctoria extract may promote hair growth better than minoxidil.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Rosemary's antioxidant content changes with the climate and season.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Human hair protein extracts can protect skin cells from oxidative stress.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.

Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Human skin can make serotonin and melatonin.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.