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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

EDA2R gene linked to hair loss.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Mouse genital development depends on male or female hormones for specific features.

A gene called HDAC9 might be a new factor in male-pattern baldness.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Mice with human gene experienced hair loss when treated with DHT.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.