research Efficacy of Metformin Therapy in Adolescent Girls with Androgen Excess: Relation to Sex Hormone-Binding Globulin and Androgen Receptor Polymorphisms
Metformin works better for adolescent girls with PCOS who have certain genetic variations.
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research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research Advances in Mitochondria-Centered Mechanism Behind the Roles of Androgens and Androgen Receptor in the Regulation of Glucose and Lipid Metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Androgens Induce Sebaceous Differentiation in Sebocyte Cells Expressing a Stable Functional Androgen Receptor
Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
research Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Therapeutic Hotline: Genetic Variations in the Androgen Receptor Gene and Finasteride Response in Women with Androgenetic Alopecia Mediated by Epigenetics
Women with greater androgen sensitivity respond better to finasteride for hair loss.
research Ayurveda-Based Botanicals as Therapeutic Adjuvants in Paclitaxel-Induced Myelosuppression
Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.
research Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice
Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Treatment of Tourette’s Syndrome With Finasteride
Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.
research The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia
Scutellaria baicalensis extract and baicalin may help prevent hair loss.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
research Effects of Heavy Ions on Rabbit Tissues: Damage to the Forebrain
Heavy ions cause significant damage to rabbit forebrains, similar to other radiation effects.
research Structural Analysis of the Outermost Hair Surface Using TOF-SIMS with Gas Cluster Ion Beam Sputtering
The hair's outermost surface has multiple layers of lipids and proteins.
research Protective Trend of Anti-Androgen Therapy During the COVID-19 Pandemic: A Meta-Analysis
Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.
research The Immunological Association Between Alopecia Areata and Respiratory Diseases: A Systematic Review
People with alopecia areata may also have allergic rhinitis and should be checked for respiratory allergies.
research The Identification of Molecular Mechanisms from Bioactive Compounds in Sansevieria Trifasciata Plant as Anti-Alopecia: In-Silico Approach
Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.
research Androgenetic Alopecia in Men: An Update on Genetics
Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.
research QSAR Analysis of a Series of Hydantoin-Based Androgen Receptor Modulators and Corresponding Binding Affinities
Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
research Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Male-Pattern Baldness Susceptibility Locus at 20p11
Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
research Advanced Intelligent Systems for Surgical Robotics
Surgical robots have improved but still can't perform tasks or make decisions on their own.
research Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research Effects of Aromatase Inhibitors on Human Osteoblast and Osteoblast-Like Cells: A Possible Androgenic Bone Protective Effect Induced by Exemestane
Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Male Pattern Baldness: Current Treatments, Future Prospects
Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.