11 citations
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January 2021 in “British Journal of Dermatology” This report describes a new case of syndromic ichthyosis caused by compound heterozygous mutations in AP1B1, detailing the associated clinical features and molecular consequences in the patient.
December 2023 in “Clinical Cosmetic and Investigational Dermatology” This case report describes an 8-year-old boy in Saudi Arabia diagnosed with IFAP syndrome, highlighting its distinct characteristics and distinguishing features from similar conditions, and notes successful genetic confirmation of the disorder.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, UPA at doses of 15 mg and 30 mg showed higher efficacy than placebo for treating severe alopecia areata in adults and adolescents over 24 weeks, with a safety profile similar to approved uses.
August 2017 in “Seoul National University Open Repository (Seoul National University)” The study investigated the role of Aminoacyl-tRNA synthetase interacting multifunctional protein 1 (AIMP1) in hair follicle stem cell proliferation and its potential as a treatment for alopecia. AIMP1, when dissociated from the multi-tRNA synthetase complex, was found to be secreted by dermal papilla cells in a sonic hedgehog (Shh) signal-dependent manner. This secretion increased the proliferation of CD34+ hair follicle stem cells by promoting the wnt signaling pathway through inhibition of sFRP1, a known wnt antagonist. The research demonstrated that the N-terminal fragment of AIMP1 could be developed into a therapeutic peptide for hair loss. When applied topically to depilated mice, this peptide significantly accelerated hair growth, especially when formulated with carbomer. The findings highlighted a novel mechanism of AIMP1 action and its potential application in alopecia treatment.
16 citations
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October 2004 in “Journal of Investigative Dermatology” This study found that normal human melanocytes can be protected from apoptosis through both PI 3-kinase/Akt-dependent and independent pathways, with insulin and TPA offering nearly complete protection.
September 2020 in “Himalayan Journal of Health Sciences” This review summarizes the diverse pharmacological activities of papaya leaf extract, highlighting its strong medicinal properties and potential cosmetic applications, but reports no new clinical results.
November 2017 in “The Philippine journal of veterinary medicine/Philippine Journal of Veterinary Medicine” This study found that aquapuncture analgesia using chili pepper decoction resulted in more complete wound healing and increased hair growth compared to distal paravertebral nerve block in goats after exploratory laparotomy.
1 citations
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March 2000 in “PubMed” This case report describes a 16-year-old boy who developed male androgenetic alopecia with a sisaipho pattern, possibly representing a rare, wave-like evolution of alopecia areata.
31 citations
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January 2014 in “International Journal of Trichology” This review summarizes the anatomy and physiology of the arrector pili muscle and discusses its potential role in hair loss disorders, reporting no new clinical results.
September 2026 in “Apollo Medicine” In this case report, researchers observed that a 35-year-old male with alopecia universalis achieved full regrowth of scalp, eyebrow, and facial hair with oral upadacitinib treatment after previous therapies failed to provide lasting relief.
5 citations
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March 2017 in “Journal of Dermatology” This survey reported that 37.6% of male AGA patients were satisfied with their treatments, with the highest satisfaction for 5-alpha-reductase inhibitors, and revealed differing perceptions between physicians and patients about AGA's impact on confidence and treatment involvement.
71 citations
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January 2011 in “Orphanet Journal of Rare Diseases” This article reviews IFAP syndrome, an X-linked genetic disorder characterized by ichthyosis follicularis, alopecia, and photophobia, and reports no new clinical findings.
January 2024 in “Biological & clinical sciences research journal” This review of 355 articles found that apigenin, a compound found in many plants and vegetables, is mainly researched for its anti-inflammatory, neuroprotective, and anti-cancer properties, with enhanced efficacy when combined with allopathic drugs.
January 2017 in “IMC Journal of Medical Science” This case report describes a 26-year-old man from Bangladesh diagnosed with autoimmune polyendocrine syndrome type 1, a rare endocrine disorder involving adrenocortical insufficiency, hypoparathyroidism, and mucocutaneous candidiasis.
35 citations
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March 2014 in “British Journal of Dermatology” This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
February 2026 in “International Journal of Dermatology” This consensus provides a framework for standardized diagnosis and treatment of alopecia areata in the Asia Pacific region, recommending specific therapies based on age and disease severity.
9 citations
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July 1993 in “Archives of dermatology” This report describes ten cases of pityriasis amiantacea to raise awareness of this uncommon scalp condition, highlighting its negative test findings and its uncertain association with other skin diseases.
November 2025 in “Journal of Investigative Dermatology” AMP-303 injections can increase hair growth in androgenetic alopecia with minimal side effects.
January 2025 in “Dermatology Online Journal” The man's hair loss and skin papules were diagnosed as atrichia with papular lesions, not alopecia areata universalis.
52 citations
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December 2014 in “Journal of Dermatological Science” Apremilast may help treat hair loss in alopecia areata.
17 citations
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November 2013 in “American Journal of Primatology” This study reported species and demographic differences in alopecia rates among macaques, with the highest rates in pigtail macaques and noted age-related improvements in alopecia scores.
2 citations
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January 2007 
May 2024 in “FEBS open bio” In this study, testing Annurca apple extract on human follicle dermal papilla cells indicated its potential to prevent patterned hair loss by reducing oxidative stress and increasing factors involved in hair growth.
April 2024 in “Demiroglu Science University Florence Nightingale Journal of Medicine” This review highlights the role of the APCDD1 gene and associated pathways in hair follicle biology, offering new perspectives on genetic contributors to hair loss and suggesting potential avenues for developing targeted treatments and preventive strategies.
226 citations
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January 2006 in “International review of cytology” Keratin-associated proteins are crucial for hair strength and structure.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
July 2015 in “Hair transplant forum international” This article summarizes the events and discussions from the 4th Scientific Meeting of the Asian Association of Hair Restoration Surgeons held in Bangkok, reporting no new research findings.
July 2025 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This study described the clinical characteristics of 18 pediatric patients with alopecia areata at a hospital in Denpasar from 2021 to 2023, finding equal gender distribution and hair loss as the most common symptom, with onset typically within 1–6 months.
42 citations
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January 2017 in “Genes” This study observed that genetic variation in the ovine KRTAP22-1 gene is linked to increased wool yield and decreased fiber curvature in sheep, indicating its potential use in breeding programs.