May 2025 in “The Journal of Rheumatology” In this case report, researchers describe a rare instance of bullous lupus presenting with severe esophageal involvement in a 42-year-old woman, highlighting the significant diagnostic and therapeutic challenges encountered in such cases despite successful treatment with immunosuppressive therapy.
May 2025 in “The Journal of Rheumatology” This case report describes a woman whose initial presentation of SLE was persistent watery diarrhea, diagnosed as lymphocytic enterocolitis, and shows that immunosuppressive therapy resulted in symptom relief.
This study found that olive leaves extract significantly decreased prostate index, serum PSA, testosterone, and DHT levels in male rats with testosterone-induced benign prostatic hyperplasia, and showed potential as a therapeutic option due to its positive effects on prostate histology and antioxidant activity.
8 citations
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November 2012 in “Blood” This study observed that the incidence of hair loss as a spontaneously reported side effect of novel oral anticoagulant therapy is approximately 4.4 per 100 patient years.
June 2023 in “Journal of Cosmetic Dermatology” This study found that a combination therapy of autologous platelet-rich plasma and non-cross-linked hyaluronic acid increased hair density significantly in women with female androgenetic alopecia, without serious adverse effects.
1 citations
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September 2023 in “Stem cell research & therapy” This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.
1 citations
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February 2023 in “International Journal of Molecular Sciences” This review discusses various therapeutic roles of melatonin, particularly its antioxidant and sleep-regulating properties, for skin and scalp conditions, and reports no new clinical results.
This study utilized the USFDA AERS to identify significant associations between various medications—such as anti-osteoporotic drugs and phenytoin—and gingival disorders, noting emergent signals with finasteride, COVID-19 vaccine, and levothyroxine, suggesting a need for awareness of oral side effects.
13 citations
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September 2023 in “Medical Gas Research” This review explores the molecular mechanisms and potential roles of nitric oxide in COVID-19 therapy, but provides no new clinical results.
December 2024 in “IntechOpen eBooks” This source discusses drug repurposing, which seeks new therapeutic uses for existing drugs, emphasizing its benefits like faster development, reduced costs, and novel treatments for unmet medical needs. The chapter outlines current trends and future perspectives in drug discovery through repurposed drugs.
22 citations
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February 2024 in “Heliyon” This review discusses the potential of fibrinolytic enzymes from various sources, especially fermented foods, for their therapeutic use in cardiovascular diseases and emphasizes the need for further research on those from non-Asian regions to optimize discovery and application.
15 citations
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March 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that fucoidan significantly inhibited lung cancer cell phenotypes while sparing normal cells and altered gene expression, suggesting its potential for lung cancer therapy.
6 citations
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July 2025 in “Advanced Materials” This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.
February 2024 in “European heart journal. Case reports” This case report highlights the need for a multidisciplinary approach in managing complex cardio-obstetric patients, as demonstrated by a pregnant woman with a large pericardial effusion successfully treated with a surgical pericardial window.
3 citations
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April 1989 in “Drug Information Journal” Side effects of drugs can lead to the discovery of new treatments.
January 2025 in “International Journal of Advancement in Life Sciences Research” In this cross-sectional study at a hospital in Nandyala, researchers identified nine drugs with potential new uses, noting that Aspirin and Dapagliflozin were most frequently repurposed, and observed changes in indications, dosage, and frequency, suggesting further clinical validation is needed for safety and efficacy.
48 citations
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August 2022 in “Chemical Biology & Drug Design” This review outlines computational strategies, including chemogenomics and drug repositioning, for coronavirus drug discovery and reports no new clinical findings; the authors highlight the advantages of these methods in rapidly identifying therapeutic candidates.
9 citations
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August 2024 in “Frontiers in Pharmacology” This review evaluates the potential of natural products and medicinal plants for myocardial infarction treatment, highlighting their therapeutic promise and mechanisms such as reducing oxidative stress and inflammation, but reports no new clinical results.
3 citations
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October 2020 in “Case Reports in Veterinary Medicine” This case report describes the first documented occurrence of a free-floating left atrial thrombus in a dog, highlighting the lack of specific therapeutic strategies for treating intracardiac thrombi in dogs.
2 citations
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September 2025 in “Journal of Clinical Medicine” This review highlights the promise of small extracellular vesicles (sEVs) as biomarkers for sepsis, emphasizing their potential to improve early detection and guide therapeutic decisions by reflecting the immune status and pathogen presence in patients.
2 citations
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January 2025 in “International Journal of Molecular Sciences” This study found that chitosan nanoparticles containing Cordyceps militaris effectively reduced lung damage in mice exposed to fine particulate matter (PM2.5) by decreasing oxidative stress and preserving lung barrier integrity, suggesting potential as a therapeutic candidate for PM2.5-induced lung diseases.
27 citations
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June 2015 in “Revista Brasileira de Farmacognosia” This review discusses the traditional uses, pharmacology, clinical applications, and toxicology of Carthami flos but reports no new clinical results, aiming to inform further research on its medicinal potential.
24 citations
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October 2017 in “Biomolecules” This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.
12 citations
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January 2020 in “touchREVIEWS in Endocrinology” Testosterone may both worsen and protect against COVID-19 effects in men.
3 citations
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June 2022 in “GSC Biological and Pharmaceutical Sciences” This study reported that methanolic extracts of Capparis decidua fruits showed significant in vitro thrombolytic activity, suggesting their potential as a dietary health supplement for preventing thrombotic cardiovascular diseases.
1 citations
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May 2025 in “The Journal of Rheumatology” In this case report, researchers described a 48-year-old man with systemic lupus erythematosus who developed a fungus ball (aspergilloma) within a tuberculosis cavity, a complication rarely reported in such patients, emphasizing the role of CT scans in diagnosis and the potential need for surgical intervention.
May 2025 in “The Journal of Rheumatology” In this case report, researchers detailed the clinical management and positive outcome of a 62-year-old woman with catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus, highlighting the potential effectiveness of Eculizumab in achieving disease remission and maintaining stability over 18 months.
May 2025 in “The Journal of Rheumatology” In this case report, a 64-year-old woman diagnosed with both NMOSD and SLE showed mild improvement in vision and recovered from thrombocytopenia after treatment with glucocorticoids and Rituximab, highlighting the importance of accurate diagnosis and tailored treatment for overlapping autoimmune disorders.
May 2025 in “The Journal of Rheumatology” This case report highlights a rare instance of diffuse alveolar hemorrhage in a patient with catastrophic antiphospholipid syndrome, emphasizing the importance of early recognition and multidisciplinary management.
February 2023 in “Asian journal of pharmaceutical research and development” This survey reports on the types and extraction factors of flavonoids in three aquatic plants from Iraqi marshlands but notes limited information on individual flavonoid profiles and their biological impacts.