research Optimizing Treatment Management of Trastuzumab Deruxtecan in Clinical Practice of Breast Cancer
Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.
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research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Propylthiouracil-Induced Alopecia Accompanying Hypohidrosis and Onychomadesis
Propylthiouracil can cause hair loss, reduced sweating, and nail issues, but stopping the drug can reverse hair and nail problems.
research Subcellular Localization of the Five Members of the Human Steroid 5α-Reductase Family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
research Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
research Central Centrifugal Cicatricial Alopecia: An Approach to Diagnosis and Management
Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research A Critical Review on Obstetric Follow-Up of Women Affected by Systemic Lupus Erythematosus
Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.
research JAK Inhibitors in Dermatology: The Promise of a New Drug Class
JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
research Disruption of Tubular Flcn Expression as a Mouse Model for Renal Tumor Induction
Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
research A Rare Case of Costovertebral Arthritis in Systemic Lupus Erythematosus
Costovertebral arthritis can cause chronic back pain in SLE patients and needs thorough evaluation.
research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
research New Potential Chemotherapy for Ovarian Cancer: Combined Therapy with WP 631 and Epothilone B
The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.
research Mesalazine in the Treatment of Extensive Alopecia Areata: A New Therapeutic Option?
Mesalazine may help treat extensive alopecia areata effectively.
research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
research Hair Loss in Women: Comprehensive Overview and Emotional Impact
The document concludes that hair loss in women is complex, often linked to aging, health conditions, and nutritional deficiencies, and emotional impacts should not be underestimated.
research Cutaneous Polyarteritis Nodosa Presenting With Digital Gangrene And Breast Ulcer
A young woman with severe symptoms of CPAN improved with intensive treatment but needed a leg amputation.
research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research The Anti-Atopic Lotions Containing Fucoidan Extracted from Ecklonia Cava Impact on Hairless Mice with Atopic Dermatitis
Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.
research Bexxar, Iodine I 131 Tositumomab, Effective in Long-Term Follow-Up of Non-Hodgkin's Lymphoma
Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using Soft Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Cyclophosphamide: As Bad as Its Reputation? Long-Term Single Centre Experience of Cyclophosphamide Side Effects in the Treatment of Systemic Autoimmune Diseases
Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
research The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway
Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
research Selected Topics in Pediatric Hair Loss
The document concludes that early diagnosis and treatment are key for pediatric hair loss disorders, and addressing the emotional effects on children is important.
research Temperature-Sensitive Hydrogel Releasing Pectolinarin Facilitate Scarless Wound Healing
A hydrogel releasing pectolinarin speeds up wound healing and reduces scarring.
research Minoxidil
Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
research Nanocarriers for Improved Delivery of Angiotensin-(1-7)
Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.